An investigation of the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan, China

Meng YuLin; Zhang HaiYan; Song BaoGuo; Zhou HuiLan; Jin XiuPing; Shi GuoHui

doi:10.3969/j.issn.1001-5256.2017.12.024

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Dec. 2017

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Article Navigation > Journal of Clinical Hepatology > 2017 > 33(12): 2376-2380

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An investigation of the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan, China

DOI: 10.3969/j.issn.1001-5256.2017.12.024

The Affiliated Hospital of North China University of Science and Technology

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Received Date: 2017-08-15
Published Date: 2017-12-20

Abstract

Abstract

Objective To investigate the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan, China, and to provide a reasonable basis for the prevention and treatment of fatty liver disease. Methods The clinical data of 12 808 individuals who underwent physical examination in Tangshan from March 2014 to February 2016 were collected, and among these individuals, 3540 had fatty liver disease. The data including age, sex, body mass index ( BMI) , fasting plasma glucose ( FPG) , total cholesterol ( TC) , triglyceride ( TG) , low-density lipoprotein cholesterol ( LDL-C) , and liver ultrasound findings were analyzed. The t-test was used for comparison of continuous data between groups and the chi-square test was used for comparison of categorical data between groups. Results Of all 7151 male individuals who underwent physical examination, 2750 ( 38. 46%) had fatty liver disease, and of all 5657 female individuals, 790 ( 13. 96%) had fatty liver disease; there was a significant difference in the prevalence rate of fatty liver disease between male and female individuals ( χ2= 947. 25, P < 0. 01) . There was a significant difference in the detection rate of fatty liver disease between male and female individuals in each age group of 18-29, 30-39, 40-49, and ≥50 years ( χ2= 337. 58, 474. 06, 449. 38, and 12. 86, all P <0. 01) . There was a significant difference in the detection rate of fatty liver disease between male or female individuals with different BMIs[obese ( BMI ≥28) , overweight ( 24≤BMI < 28) , and normal ( BMI < 24) ] ( χ2= 1104. 01 and 500. 23, both P < 0. 01) . In the three groups of obese ( BMI ≥28) , overweight ( 24≤BMI < 28) , and normal ( BMI < 24) individuals who underwent physical examination, there was a significant difference in the detection rate of fatty liver disease between male and female individuals in each group ( χ2= 71. 24, 87.97, and 323. 84, all P < 0. 01) . Male and female individuals with obesity ( BMI ≥28) and overweight ( 24≤BMI < 28) had a significantly higher detection rate of fatty liver disease than those with normal BMI ( both P < 0. 01) . There were significant differences in FPG, TC, TG, and LDL-C between the fatty liver group and the non-fatty liver group ( t = 17. 482, 13. 698, 22. 133, and 27. 334, all P < 0. 001) . In male individuals who underwent physical examination, there were significant differences in FPG, TC, TG, and LDL-C between the individuals with and without fatty liver disease ( t = 11. 288, 8. 652, 11. 671, and 20. 118, all P < 0. 01) ; in female individuals, there were also significant differences in FPG, TC, TG, and LDL-C between the individuals with and without fatty liver disease ( t = 16. 816, 5. 532, 15. 154, and 18. 507, all P < 0. 01) . Conclusion Among the adults undergoing physical examination in Tangshan, male adults have a significantly higher prevalence rate of fatty liver disease than female adults. Overweight or obesity, hyperlipidemia, and abnormal glucose metabolism are major causes of fatty liver disease.
- fatty liver,
- prevalence,
- data interpretation statistical

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References(23)

References

[1]CLARK JM, DIEHL AM.Defining non-alcoholic fatty liver disease:implications for epidemiologic studies[J].Gastroenterology, 2003, 124 (1) :248-250.

[2]FAN JG, FARRELL GC.Epidemiology of non-alcoholic fatty liver disease in China[J].J Hepatol, 2009, 50 (1) :204-210.

[3]Joint Committee for Developing Chinese Guidelines on prevention and treatment of dyslipidemia in adults.Chinese guidelines on prevention and treatment of dyslipidemia in adults[J].Chin J Cardiol, 2007, 35 (5) :390-419. (in Chinese) 中国成人血脂异常防治指南制订联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志, 2007, 35 (5) :390-419.

[4]Report of the expert committee on the diagnosis and classification of diabetes mellitus[J].Diabetes Care, 1997 (7) :1183-1197.

[5]Group of Fatty Liver and Alcoholic Liver Diseases, Society of Hepatology, Chinese Medical Association.Guidelines for management of non-alcoholic fatty liver disease[J].J Clin Hepatol, 2010, 26 (2) :120-124. (in Chinese) 中华医学会肝脏病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南[J].临床肝胆病杂志, 2010, 26 (2) :120-124.

[6]FAN JG, YAN SY.Metabolic syndrome and fatty liver[J].J Clin Hepatol, 2016, 32 (3) :407-410. (in Chinese) 范建高, 颜士岩.代谢综合征与脂肪肝[J].临床肝胆病杂志, 2016, 32 (3) :407-410.

[7]ZHENG XY, WANG YH, LUO R, et al.Association research between metabolism syndrome and fatty liver of 5782 health examination cohort in Chongqing[J].J Chongqing Med Univ, 2010, 35 (5) :727-730. (in Chinese) 郑晓雅, 王永红, 罗蓉, 等.重庆市5782例体检人群代谢综合征与脂肪肝的相关性研究[J].重庆医科大学学报, 2010, 35 (5) :727-730.

[8]GU WG, FENG JY.Prevalence of nonalcoholic fatty liver disease in overweight and obese populations and related risk factors[J].Gansu Med J, 2015, 34 (2) :109-112. (in Chinese) 顾伟根, 冯静亚.超重和肥胖人群非酒精性脂肪肝的流行现状及相关危险因素分析[J].甘肃医药, 2015, 34 (2) :109-112.

[9]HE LY, GUO LJ.Metabolic features and adjustment of female blood lipids[J].Clin Focus (Med J) , 2006, 21 (23) :1689-1691. (in Chinese) 何立芸, 郭丽君.女性血脂代谢特点及处理[J].临床荟萃, 2006, 21 (23) :1689-1691.

[10]JIN P, DING YY, WANG BY, et al.Epidemiological survey of prevalence of fatty liver disease and its risk factors in urban population of northeast China[J].Chin J Gastroenterol Hepatol, 2011, 20 (7) :617-620, 623. (in Chinese) 金萍, 丁媛媛, 王炳元, 等.东北地区城市脂肪肝的患病率及其危险因素的流行病学调查[J].胃肠病学和肝病学杂志, 2011, 20 (7) :617-620, 623.

[11]WANG HW, ZOU CC, LI JH, et al.Risk factors for fatty liver disease and related nursing measures:an analysis of 8884 individuals undergoing physical examination in Shenzhen, China[J].J Nurs, 2013, 20 (5A) :38-41. (in Chinese) 王红卫, 邹长翠, 李瑾虹, 等.深圳市8884例体检者脂肪肝危险因素分析及护理[J].护理学报, 2013, 20 (5A) :38-41.

[12]CHEN QY.Analysis of the prevalence of fatty liver in shantou area[J].Guangzhou Med J, 2014, 45 (6) :72-75. (in Chinese) 陈秋妍.汕头地区脂肪肝患病现状分析[J].广州医药, 2014, 45 (6) :72-75.

[13]QIAO LN, DAI GR, ZHANG J, et al.An epidemiological survey of prevalence and risk factors for fatty liver disease in adults residing in Yan'an, China[J].J Clin Hepatol, 2015, 10 (1) :82-87. (in Chinese) 乔丽娜, 戴光荣, 张锦, 等.延安地区成人脂肪肝患病率及其危险因素的探讨[J].临床肝胆病杂志, 2015, 10 (1) :82-87.

[14]NIU CY, YAN R, TIAN Y, et al.The prevalence of fatty liver disease and its relationship with metabolic syndrome[J].J Clin Hepatol, 2010, 26 (2) :167-169. (in Chinese) 牛春燕, 闫蓉, 田宇, 等.乌鲁木齐地区脂肪肝发病率及非酒精性脂肪肝与代谢综合征的关系[J].临床肝胆病杂志, 2010, 26 (2) :167-169.

[15]XIE WB, WANG XL, LUO R, et al.The distribution of fatty liver diseases among adult residents in Chongqing by B-ultrasound[J].JChongqing Med Univ, 2010, 35 (10) :1601-1603. (in Chinese) 谢微波, 王小林, 罗蓉, 等.重庆市成人居民脂肪肝分布特点[J].重庆医科大学学报, 2010, 35 (10) :1601-1603.

[16]FAN JG, ZHU J, LI XJ, et al.Epidemiological survey of prevalence of fatty liver and its risk factors in a general adult population of Shanghai[J].Chin J Hepatol, 2005, 13 (2) :83-88. (in Chinese) 范建高, 朱军, 李新建, 等.上海市成人脂肪肝患病率及其危险因素流行病学调查[J].中华肝脏病杂志, 2005, 13 (2) :83-88.

[17]LI N, SUN WH, YUAN ZH.Fatty liver of urban residents in Gan Zhou city and its risk factors analysis[J].J Gannan Med Uni, 2013, 33 (2) :273-275. (in Chinese) 李宁, 孙蔚华, 袁招红.赣州市城镇居民脂肪肝患病率及其危险因素分析[J].赣南医学院学报, 2013, 33 (2) :273-275.

[18]LI GH.Prevalence of fatty liver disease among residents in Shijiazhuang, China and related risk factors[D].Hebei:Hebei Medical University, 2012. (in Chinese) 李桂红.石家庄市人群脂肪性肝病流行率及相关因素研究[D].河北:河北医科大学, 2012.

[19]ZHI LX, DUAN DS, HAN JW, et al.Prevalence of fatty liver disease in coastal towns in Hebei Province, China and related risk factors[J].Hebei Med J, 2015, 37 (1) :114-116. (in Chinese) 智利霞, 段冬生, 韩俊武, 等.河北沿海城镇脂肪肝患病率及危险因素调查研究[J].河北医药, 2015, 37 (1) :114-116.

[20]LI YP, ZHANG X.Risk factors for different degrees of fatty liver disease[J].Mod Med Health, 2015, 31 (14) :2167-2169. (in Chinese) 李艳萍, 张霞.不同程度脂肪肝的相关危险因素分析[J].现代医药卫生, 2015, 31 (14) :2167-2169.

[21]JIA Y, FU YJ, LIU XY, et al.Research progress of alcoholic fatty liver disease in China[J].Chin J Gastroenterol Hepatol, 2014, 23 (4) :376-379. (in Chinese) 贾艳, 付怡静, 刘晓阳, 等.我国酒精性脂肪肝的研究进展[J].胃肠病学和肝病学杂志, 2014, 23 (4) :376-379.

[22]AHMED MH, HUSAIN NE, ALMOBARAK AO.Non-alcoholic fatty liver disease and risk of diabetes and cardiovascular disease:what is important for primary care physicians[J].J Family Med Prim Care, 2015, 4 (1) :45-52.

[23]XIN SL, XU KS.A new understanding of the pathogenesis of nonalcoholic fatty liver disease[J].J Clin Hepatol, 2017, 33 (8) :1581-1583. (in Chinese) 辛晟梁, 徐可树.非酒精性脂肪性肝病发病机制新认识[J].临床肝胆病杂志, 2017, 33 (8) :1581-1583.

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An investigation of the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan, China

DOI: 10.3969/j.issn.1001-5256.2017.12.024

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An investigation of the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan, China

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