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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 11
Nov.  2017
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Article Contents

Research advances in the role of platelets in liver diseases

DOI: 10.3969/j.issn.1001-5256.2017.11.043
  • Received Date: 2017-05-09
  • Published Date: 2017-11-20
  • Chronic liver diseases such as liver fibrosis and liver cirrhosis have a complex pathogenesis and are the result of interaction between various cells, cytokines, and matrix in the liver.The traditional viewpoints believe that platelets are mainly involved in hemostasis and coagulation.In recent years, more and more articles have reported that platelets contain molecular protein for hemostasis and growth factors for organ development and tissue regeneration/repair;moreover, platelets are closely associated with the development and progression of chronic liver diseases such as liver fibrosis and liver cirrhosis and regeneration of liver tissue.They also play a key role in liver homeostasis and pathology.At present, many research findings have been achieved in the association between platelets and the signaling pathways of liver fibrosis and liver regeneration, suggesting that platelets may become a new target for the treatment of chronic liver diseases.

     

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