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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 11
Nov.  2017
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Research advances in primary biliary cholangitis complicated by osteoporosis

DOI: 10.3969/j.issn.1001-5256.2017.11.039
  • Received Date: 2017-08-18
  • Published Date: 2017-11-20
  • Osteoporosis is a common complication of primary biliary cholangitis (PBC) with a relatively high prevalence rate and a high risk of bone fracture.The pathogenesis of osteoporosis remains unknown.This article reviews the latest advances in the pathogenesis and treatment of osteoporosis in PBC.Studies have shown that osteoporosis in PBC has various causes, including increased bone absorption and reduced bone formation due to many factors.Although many drugs have been used in clinical practice, until now, bisphosphonates are still the most effective drugs.Long-term systematic studies are needed in the future to clarify their effects on fracture in PBC patients.

     

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