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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 1
Jan.  2017
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Article Contents

Role of serum abnormal prothrombin protein induced by vitamin K absence or antagonist-Ⅱ in development and progression of hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2017.01.040
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  • Published Date: 2017-01-20
  • Early diagnosis of hepatocellular carcinoma( HCC) using tumor markers is very important for long- term survival. This article elaborates on the value and high sensitivity and specificity of protein induced by vitamin K absence or antagonist- Ⅱ( PIVKA- Ⅱ) in the early diagnosis,prognostic evaluation,and recurrence prediction of HCC. Its combination with alpha- fetoprotein can significantly increase the early diagnostic rate of HCC. It is pointed out that dynamic measurement of PIVKA- Ⅱ level can assist the correct evaluation of the development,progression,invasion / metastasis,and recurrence of HCC and can be used as an important marker for the prognosis of HCC.

     

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