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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 1
Jan.  2017
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Article Contents

Safety of fast track surgery in pancreaticoduodenectomy: a Meta-analysis

DOI: 10.3969/j.issn.1001-5256.2017.01.026
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  • Published Date: 2017-01-20
  • Objective To investigate the safety and clinical effect of fast track surgery in pancreaticoduodenectomy,one of the most complex surgeries in general surgery. Methods The Chinese and foreign databases were searched for articles on the application of fast tract surgery in pancreaticoduodenectomy published from January 1994 to April 2016. Two researchers evaluated the quality of the articles which met the inclusion criteria and extracted related data. Stata 12. 0 software was used to analyze the overall incidence rate of complications and the incidence rates of pancreatic leakage and gastrointestinal emptying disorder,and the Begg rank correlation test and Egger linear regression method were used to investigate publication bias. Results The fast track surgery group had a significantly lower overall incidence rate of complications than the conventional group( RR = 0. 748,95% CI: 0. 680- 0. 824,P < 0. 001). There was no significant difference in the incidence rate of pancreatic leakage between the two groups( RR = 0. 894,95% CI: 0. 734- 1. 089,P = 0. 266). The fast track surgery group had a significantly lower incidence rate of gastrointestinal emptying disorder than the conventional group( RR = 0. 520,95% CI: 0. 400- 0.670,P < 0. 001). Conclusion Fast track surgery is safe and effective in pancreaticoduodenectomy,but the application of some measures in fast track surgery still needs more medical evidence.

     

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