中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 7
Jul.  2016
Turn off MathJax
Article Contents

Research advances in sinusoidal obstruction syndrome

DOI: 10.3969/j.issn.1001-5256.2016.07.050
  • Published Date: 2016-07-20
  • Sinusoidal obstruction syndrome( SOS) is a sinusoidal or small venous fibrous occlusive disease. This article reviews the research advances in the etiology,pathogenesis,clinical manifestations,auxiliary examinations,and treatment of SOS,and points out that the pathogenesis of SOS remains unknown and there are no specific therapeutic methods. How to identify SOS and provide intervention and treatment as early as possible becomes the hot research topic.

     

  • loading
  • [1]DIGNAN FL,WYNN RF,HADZIC N,et al.BCSH/BSBMTguideline:diagnosis and management of veno-occlusive diseas(sinusoidal obstruction syndrome)following haematopoietic stem cell transplantation[J].Br J Haematol,2013,163(4):444-457.
    [2]MOHTY M,MALARD F,ABECASSIS M,et al.Sinusoidal obstruction syndrome/veno-occlusive disease:current situation and perspectives---a position statement from the European Society for Blood and Marrow Transplantation(EBMT)[J].Bone Marrow Transplant,2015,50(6):781-789.
    [3]WANG JY,GAO H.Tusanqi and hepatic sinusoidal obstruction syndrome[J].J Dig Dis,2014,15(3):105-107.
    [4]WANG XX,QI XS,GUO XZ.Tusanqi-related sinusoidal obstruction syndrome in China:a systematic review of the literatures[J].Medicine(Baltimore),2015,94(23):e942.
    [5]HILL KR,RHODES K,STAFFORD JL,et al.Serous hepatosis:a pathogenesisos hepatic fibrosis in Jamaican children[J].Br Med J,1953,1(4802):117-122.
    [6]SHULMAN HM,McD ONALD GB,MATTHEWS D,et al.An analysis of hepatic veno-occlusive disease and centrilobular hepatic degeneration following bone marrow transplantation[J].Gastroenterology,1980,79(6):1178-1191.
    [7]de LEVE L,VALLA D,GARCIATSAO G,et al.Vascular disorders of the liver[J].Hepatology,2009,49(5):1729-1764.
    [8]CUTLER C,STEVENSON K,KIM H,et al.Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation[J].Blood,2008,112(12):4425-4431.
    [9]RUBBIABRANDT L,TAUZIN S,BREZAULT C,et al.Gene expression profiling provides insights into pathways of oxaliplatin related sinusoidal obstruction syndrome in humans[J].Mol Cancer T-her,2011,10(4):687-696.
    [10]SEIFERT C,WITTIG S,ARNDT C,et al.Heparanase polymorphisms:influence on incidence of hepatic sinusoidal obstruction syndrome in children undergoing allogeneic hematopoietic stem cell transplantation[J].J Cancer Res Clin,2014,141(5):877-885.
    [11]EFRATI E,ZUCKERMAN T,BENAMI E,et al.MTHFR C677T/A1298C genotype:a possible risk factor for liver sinusoidal obstruction syndrome[J].Bone Marrow Transplant,2014,49(5):726-727.
    [12]VREULS CP,OLDEDAMINK SW,KOEK GH,et al.Glutathione S-transferase M1-null genotype as risk factor for SOS in oxaliplatin-treated patients with metastatic colorectal cancer[J].Br JCancer,2013,108(3):676-680.
    [13]KALLIANPUR AR,HALL LD,YADAV M,et al.The hemochromatosis C282Y allele:a risk factor for hepatic veno-occlusive disease after hematopoietic stem cell transplantation[J].Bone Marrow Transplant,2005,35(12):1155-1164.
    [14]ELBAHLAWAN L,McA RTHUR J,QUASNEY MW,et al.Association of IL-1β-511 polymorphism with severe veno-occlusive disease in pediatric-matched allogeneic hematopoietic stem cell transplantation[J].J Pediatr Hematol Oncol,2012,34(3):175-179.
    [15]YANG C,FRIESS SH,DEHNER LP.Hepatic mucormycosis mimicking veno-occlusive disease:report of a case and review of the literature[J].Pediatr Dev Pathol,2016,19(2):150-153.
    [16]FAN CQ,CRAWFORD JM.Sinusoidal obstruction syndrome(hepatic veno-occlusive disease)[J].J Clin Exp Hepatol,2014,4(4):332-346.
    [17]COPPELL J,BROWN S,PERRY D.Veno-occlusive disease:cytokines,genetics,and haemostasis[J].Blood Rev,2003,17(2):63-70.
    [18]WANG XX,QI XS,GUO XZ.Sinusoidal obstruction syndrome/veno-occlusive disease:current situation and perspectives-a position statement from the European Society for Blood and Marrow Transplantation(EBMT)in 2015[J].J Clin Hepatol,2015,31(5):659-664.(in Chinese)王晓晰,祁兴顺,郭晓钟.2015年欧洲骨髓移植协作组立场声明:肝窦阻塞综合征/肝小静脉闭塞症的现状和展望[J].临床肝胆病杂志,2015,31(5):659-664.
    [19]CHEN Z,HUO JR.Hepatic veno-occlusive disease associated with toxicity of pyrrolizidine alkaloids in herbal preparations[J].Neth J Med,2010,68(6):252-260.
    [20]de LEVE LD,ITO Y,BETHEA NW,et al.Embolization by sinusoidal lining cell obstructs the microcirculation in rat sinusoidal obstruction syndrome[J].Am J Physiol Gastrointest Liver Physiol,2003,284(6):g1045-g1052.
    [21]SOON R,YEE H.Stellate cell contraction:role,regulation,and potential therapeutic target[J].Clin Liver Dis,2008,12(4):791-803.
    [22]DELEVE L,WANG X,TSAI J,et al.Sinusoidal obstruction syndrome(veno-occlusive disease)in the rat is prevented by matrix metalloproteinase inhibition 1[J].Gastroenterology,2003,125(3):882-890.
    [23]ROBINSON S,MANN J,VASILAKI A,et al.Pathogenesis of FOL-FOX induced sinusoidal obstruction syndrome in a murine chemotherapy model[J].J Hepatol,2013,59(2):318-326.
    [24]ROBINSON S,MANN D,MANAS D,et al.The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome[J].Br J Cancer,2013,109(9):2396-2403.
    [25]PENG T,ZHANG GY,LIU YL.Identification of Budd-Chiari syndrome,hepatic sinusoidal obstruction syndrome and hepatic cirrhosis[J].J Clin Hepatol,2011,27(10):1022-1026,1031.(in Chinese)彭涛,张国艳,刘玉兰.布-加综合征、肝血窦阻塞综合征与肝硬化的鉴别[J].临床肝胆病杂志,2011,27(10):1022-1026,1031.
    [26]CHAO N.How I treat sinusoidal obstruction syndrome[J].Blood,2014,123(26):4023-4026.
    [27]GAO H,RUAN JQ,CHEN J,et al.Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloidhepatic sinusoidal obstruction syndrome[J].Drug Des Devel Ther,2015,9:4861-4868.
    [28]LEE J,LEE K,SEOL M,et al.Plasminogen activator inhibitor-1is an independent diagnostic marker as well as severity predictor of hepatic veno-occlusive disease after allogeneic bone marrow transplantation in adults conditioned with busulphan and cyclophosphamide[J].Br J Haematol,2002,118(4):1087-1094.
    [29]LEE JH.Biomarkers for hepatic sinusoidal obstruction syndrome after hematopoietic cell transplantation[J].Blood Res,2015,50(3):123-125.
    [30]SHAO H,CHEN HZ,ZHU JS,et al.Computed tomography findings of hepatic veno-occlusive disease caused by Sedum aizoon with histopathological correlation[J].Braz J Med Biol Res,2015,48(12):1145-1150.
    [31]DUMONT CH,LAMBERT M,van BEERS BE.MR imaging finding in a patient with hepatic veno-occlusive disease[J].Acta Gastroenterol Bels,2004,67(2):236-238.
    [32]APPERLEY J,CARRERAS E,GLUCKMAN T,et al.The EBMT-ESH handbook on haemo-poietic stem cell transplantation[EB/OL].[2015-5-13].http://ebmtonline.forumservice.net/media/11/tex/content_alt/EBMT_Handbook 2012_CHAP11.pdf.
    [33]CHENG JY,WANG TL,ZHAO XY,et al.Analysis of liver specimen quality using 280 specimens obtained by routine puncture biopsy[J].Chin J Hepatol,2014,22(3):231-232.(in Chinese)程捷尧,王泰龄,赵新颜,等.280例肝穿刺标本质量调查分析[J].中华肝脏病杂志,2014,22(3):231-232.
    [34]CARRERAS E.How I manage sinusoidal obstruction syndrome after haematopoietic cell transplantation[J].Br J Haematol,2015,168(4):481-491.
    [35]YOON JH,MIN WS,KIM HJ,et al.Experiences of t-PA use in moderate-to-severe hepatic veno-occlusive disease after hematopoietic SCT:is it still reasonable to use t-PA?[J].Bone Marrow Transplant,2013,48(12):1562-1568.
    [36]IBRAHIM R,PERES E,DANSEY R,et al.Anti-thrombinⅢin the management of hematopoietic stem-cell transplantation-associated toxicity[J].Ann Pharmacother,2004,38(6):1053-1059.
    [37]HAUSSMANN U,FISCHER J,EBER S,et al.Hepatic veno-occlusive disease in pediatric stem cell transplantation:impact of pre-emptive antithrombinⅢreplacement and combined antithrombinⅢ/defibrotide therapy[J].Haematologica,2006,91(6):795-800.
    [38]RICHARDSON PG,HO VT,GIRALT S,et al.Safety and efficacy of defibrotide for the treatment of severe hepatic veno-occlusive disease[J].Ther Adv Hematol,2012,3(4):253-265.
    [39]RICHARDSON PG,SOIFFER RJ,ANTIN JH,et al.Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation:a multicenter,randomized,dose-finding trial[J].Biol Blood Marrow Transplant,2010,16(7):1005-1017.
    [40]RICHARDSON P,MURAKAMI C,JIN Z,et al.Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure:response without significant toxicity in a high-risk population and factors predictive of outcome[J].Blood,2002,100(13):4337-4343.
    [41]CORBACIOGLU S,CESARO S,FARACI M,et al.Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation:an open-label,phase 3,randomised controlled trial[J].Lancet,2012,379(9823):1301-1309.
    [42]HELMY A.Review article:updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome[J].Aliment Pharm T-her,2006,23(1):11-25.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2497) PDF downloads(576) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return