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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 5
May  2016
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Article Contents

Classification and diagnosis of pancreatic cystic neoplasm

DOI: 10.3969/j.issn.1001-5256.2016.05.039
  • Published Date: 2016-05-20
  • Pancreatic cystic neoplasm is a relatively rare potential neoplasm in clinical practice and has a low- grade malignancy. Pancreatic cystic neoplasm is classified as serous cystic neoplasm,mucinous cystic neoplasm,intraductal papillary mucinous neoplasm,and solid pseudopapillary neoplasm. Due to its complex pathological type and the deep location of the pancreas,patients often lack typical clinical symptoms and signs,which may easily lead to misdiagnosis or missed diagnosis. This article introduces the classification of pancreatic cystic neoplasm and research advances in serological examinations,cyst puncture and aspiration,and imaging examinations in the diagnosis of pancreatic cystic neoplasm and points out a combination of various examinations can improve the rate of confirmed diagnosis of pancreatic cystic neoplasm.

     

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  • [1]ADET A,MIQUEL R,BOMBI JA,et al.Incidence and characteristics of pancreatic cystic neoplasms[J].Gastroenterol Hepatol,2010,33(8):563-568.
    [2]WU Z,WANG Z,XU QH.Surgical treatment of pancre-atic cystic neoplasms[J].J Clin Hepatol,2015,31(5):674-677.
    [3]Italian Association of Hospital Gastroenterologists and Endoscopists;Italian Association for the Study of the Pancreas.Italian consensus guidelines for the diagnostic work-up and fol low-up of cystic pancreatic neoplasms[J].Dig Liver Dis,2014,46(6):479-493.
    [4]del CHIARO M,VERBEKE C,SALVIA R,et al.European experts con-sensus statement on cystic tumours of the pancreas[J].Dig Liver Dis,2013,45(9):703-711.
    [5]CHIN JY,PITMAN MB,HONG TS.Intraductal papillary mucinous neoplasm:clinical surveillance and management decisions[J].Semin Radiat Oncol,2014,24(2):77-84.
    [6]MOHAMADNEJAD M,ELOUBEIDI MA.CystsicL esions of the pancreas[J].Arch Iran Med,2013,16(4):233-239.
    [7]WANG CF.Diagnosis and treatment strategy of pancreatic cystic neoplasms[J].Natl Med J China,2014,94(2):81-82.(in Chinese)王成锋.胰腺囊性肿瘤的诊治策略[J].中华医学杂志,2014,94(2):81-82.
    [8]CLORES MJ,THOSANI A,BUSCAGLIA JM.Multidisciplinary diagnostic and therapeutic approaches to pancreatic cystic lesions[J].J Multidiscip Healthc,2014,7(7):81-91.
    [9]TIAN XD,WU GD,ZHUANG Y,et al.Individualized surgical treatment and prognosis of intraductal papillary mucinous neoplasms of the pancreas[J].Chin J Surg,2013,51(7):588-591.(in Chinese)田孝东,吴广东,庄岩,等.胰腺导管内乳头状黏液性肿瘤的外科治疗及预后分析[J].中华外科杂志,2013,51(7):588-591.
    [10]KAPPELI RM,MULLER SA,HUMMEL B,et al.IPMN:surgical treatment[J].Langenbeck’s Arch Surg,2013,398(8):1029-1037.
    [11]SHEN X,LU D,XU X,et al.A novel distinguishing system for the diagnosis of malignant pancreatic cystic neoplasm[J].Eur J Radiol,2013,82(11):e648-e654.
    [12]BEGER HG,SIECH M,POCH B.Duodenum-preserving total pancreat ic head resection:an organ-sparing operation technique for cystic neoplasms and non-invasive malignant tumors[J].Chirurg,2013,84(5):412-420.
    [13]BUSCARINI E,PEZZILLI R,CANNIZZARO R,et al.Italian consensus guidelines for the diagnostic work-up and follow-up of cystic pancreatic neoplasms[J].Dig Liver Dis,2014,46(6):479-493.
    [14]TALAR-WOJNAROWSKA R,PAZUREK M,DURKO L,et al.A comparative analysis of K-ras mutation and carcinoembryonic antigen in pancreatic cyst fluid[J].Pancreatoloy,2012,12(5):417-420.
    [15]HONG SK,LOREN DE,ROGART JN,et al.Targeted cyst wall puncture and aspiration during EUS-FNA increases the diagnostic yield of premalignant and malignant pancreatic cysts[J].Gastrointest Endosc,2012,75(4):775-782.
    [16]BARRESI L,TARANTINO I,TRAINA M,et al.Endoscopic ultrasound-guided fine needle aspiration and biopsy using a 22-gauge needle with side fenestration in pancreatic cystic lesions[J].Dig Liver Dis,2014,46(1):45-50.
    [17]TALUKDAR R,NAQESHWAR REDDY D.Treatment of pancreatic cystic neoplasm:surgery or conservative[J].Clin Gastroenterol Hepatol,2014,12(1):145-151.
    [18]de JONG K,van HOOFL JE,NIO CY,et al.Accuracy of preoperative workup in a prospective series of surgically resected cystic pancreatic lesions[J].Scand J Gastroenterol,2012,47(8-9):1056-1063.
    [19]BARRESI L,TARANTINO I,GRANATA A,et al.How endoscopic ultrasound morphology and endoscopic ultrasound fine needle aspiration help unlock the diagnostic puzzle[J].World J Gastrointestina Endosc,2012,4(6):247-259.
    [20]ZHOU Y,ZHOU CS.Imaging diagnosis of the cystic lesions of pancreas[J].J Med Imaging,2005,15(4):326-328.(in Chinese)周英,周存升.胰腺囊性病变的影像学诊断[J].医学影像学杂志,2005,15(4):326-328.
    [21]XU P,XU M.Clinical feature,diagnosis and treatment of pancreatic cystic lesion[J].Chin J Gastroenterol,2014,19(1):40-42.(in Chinese)徐萍,徐敏.胰腺囊性病变的临床特征和诊治分析[J].胃肠病学,2014,19(1):40-42.
    [22]XIE JW,YAO Y,WANG XY,et al.An analysis on the CT character of pancreatic cystadenoma[J].J Med Imaging,2008,18(7):819-820.(in Chinese)谢君伟,姚毅,王小燕,等.胰腺囊腺肿瘤的CT特征分析[J].医学影像学杂志,2008,18(7):819-820.
    [23]LI HM,ZHAO WD,CAI L,et al.The analysis of biological treatment of pancreatic cancer by the measurement of iodine-based image after spectral CT imaging[J].China Modern Med,2012,19(20):13-14,17.栗鸿民,赵卫东,蔡琳,等.能谱CT碘基图对胰腺癌生物治疗疗效的分析[J].中国当代医药,2012,19(20):13-14,17.
    [24]LEE HJ,KIM MJ,CHOI JY,et al.Relative accuracy of CT and MRIin the differentiation of benign from malignant pancreatic cystic lesions[J].Clin Radiol,2011,66(4):315-321.
    [25]LIMAIEM F,KHALFALLAH T,FARHAT LB,et al.Pancreatic cystic neoplasms[J].N Am J Med Sci,2014,6(8):413-417.
    [26]HIRONO S,TANI M,KAWAI M,et al.The careinoembryonic antigen level in pancreatic juice and mural nodule size are predictors of malignancy for branch duct type intraductal papillary mucinous neoplasms of the pancreas[J].Ann Surg,2012,255(3):517-522.
    [27]PUCCI MJ,JOHNSON CM,PUNJA VP,et al.Intraoperative pancreato-scopy:a valuable tool for pancreatic surgeons?[J].J Gastrointest Surg,2014,18(6):1100-1107.
    [28]TOPAZIAN M.Endoscopic ultrasound—guided drainage of pancreatic fluid collections(with video)[J].Clin Endosc,2012,45(3):337-340.
    [29]YAMAO K,YANAGISAWA A,TAKAHASHI K,et al.Clinicopathological features and prognosis of mucinous cystic neoplasm with ovarian-type stroma:a multi-institutional study of the Japan pancreas society[J].Pancreas,2011,40(1):67-71.
    [30]TANAKA M,FERNANDEZ-DEL CASTILLO C,ADSAY V,et al.International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas[J].Pancreatology,2012,12(3):183-197.
    [31]JANA T,SHROFF J,BHUTANI MS.Pancreatic cystic neoplasms:review of current knowledge,diagnostic challenges,and managementoptions[J].J Carcinog,2015,14:3.
    [32]DONAHUE TR,HINES OJ,FARRELL JJ,et al.Cystic neoplasms of the pancreas:results of 114 cases[J].Pancreas,2010,39(8):1271-1276.
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