Progress in treatment of hypersplenism in patients with post-hepatitis cirrhosis

Hypersplenism is a common complication of post-hepatitis cirrhosis,and may not need to be treated. The treatment of hypersplenism is not considered if it is not proven clinically beneficial to patients. However,there are still some patients with hypersplenism who should be treated for some reasons. This article reviews the latest progress in the therapies for hypersplenism,including splenectomy,splenic artery embolization,splenic radiofrequency ablation,liver transplantation,medication,and transjugular intrahepatic portosystemic shunt. It is demonstrated that all the above treatments have advantages and disadvantages. Minimally invasive methods,through currently preferred for hypersplenism,have not yet been clinically applied for a long period,and remain to be technically improved and supported by relevant evidence for standardization.