Clinical evaluation of endoscopic ligation with nylon snares for adenoma of the major duodenal papilla

Objective To evaluate the feasibility,safety,and follow-up results of endoscopic ligation with nylon snares for adenoma of the major duodenal papilla. Methods Twenty-three patients with adenoma of the major papilla who were treated in our hospital from January2012 to June 2014 were enrolled as subjects. All patients had biliary and pancreatic duct stents placed by endoscopic cholangiopancreatography,followed by complete ligation of tumors with nylon snares. Endoscopic follow-up evaluation of recurrence was performed regularly.Results All patients had biliary and pancreatic duct stents successfully placed and tumors successfully ligated with nylon snares in their first surgery. Endoscopic reexamination at two weeks after surgery showed that tumors were removed in all patients. Postoperative complications,cholangitis and pancreatitis,were found in one( 4. 3%) and two( 8. 7%) patients,respectively,and there were no bleeding,perforation,or death. A follow-up of more than one year in all patients showed that two patients had local recurrence of adenoma. Conclusion Endoscopic ligation with nylon snares is a safe and effective approach for treating adenoma of the major duodenal papilla.