中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2015
Turn off MathJax
Article Contents

Mirabilite umbilical compress in treatment of ascites in liver cirrhosis: a meta-analysis

DOI: 10.3969/j.issn.1001-5256.2015.06.028
  • Published Date: 2015-06-20
  • Objective To systematically evaluate the efficacy of mirabilite umbilical compress in the treatment of ascites in liver cirrhosis.Methods The literature on the treatment of cirrhotic ascites with mirabilite umbilical compress was searched in CNKI,VIP,Wanfang Data,and Pub Med databases. A meta- analysis was carried out using the random effect model. The continuous and categorical data were expressed as aas standard mean difference( SMD) and odds ratio( OR),respectively. Results A total of 11 randomized controlled trials were included. The mirabilite umbilical compress treatment group showed a significantly higher response rate of ascites( OR = 3. 19,P < 0. 0001) and significantly reduced abdominal circumference( SMD = 1. 69,P < 0. 0001) and body weight( SMD = 2. 77,P < 0. 0001) compared with the control group. After mirabilite umbilical compress treatment,alanine transaminase level was significantly decreased( SMD = 1. 92,P =0. 0009),albumin level was significantly increased( SMD =- 1. 78,P = 0. 0006),while aspartate aminotransferase and total bilirubin levels showed no significant changes( SMD = 3. 39,P = 0. 25). Conclusion Mirabilite umbilical compress is effective in the treatment of ascites in liver cirrhosis,yet its efficacy in improving liver function remains uncertain.

     

  • loading
  • [1]GINES A,FERNANDEZ-ESPARRACH G,MONESCILLO A,et al.Randomized trial comparing albumin,dextran 70,and polygeline in cirrhotic patients with ascites treated by paracentesis[J].Gastroenterology,1996,111(4):1002-1010.
    [2]GINES P,TITO L,ARROYO V,et al.Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis[J].Gastroenterology,1988,94(6):1493-1502.
    [3]ANGELI P,de BEI E,DALLA PRIA M,et al.Effects of amiloride on renal lithium handling in nonazotemic ascitic cirrhotic patients with avid sodium retention[J].Hepatology,1992,15(4):651-654.
    [4]BERNARDI M.Optimum use of diuretics in managing ascites in patients with cirrhosis[J].Gut,2010,59(1):10-11.
    [5]ANGELI P,DALLA PRIA M,de BEI E,et al.Randomized clinical study of the efficacy of amiloride and potassium canrenoate in nonazotemic cirrhotic patients with ascites[J].Hepatology,1994,19(1):72-79.
    [6]ANGELI P,FASOLATO S,MAZZA E,et al.Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis:results of an open randomised clinical trial[J].Gut,2010,59(1):98-104.
    [7]QI XS,HAN GH,FAN DM.Recent advances in the clinical application of transjugular intrahepatic portosystemic shunt for the treatment of portal hypertension[J].J Intervent Radiol,2011,20(6):499-504.(in Chinese)祁兴顺,韩国宏,樊代明.经颈内静脉肝内门体分流术临床应用新进展[J].介入放射学杂志,2011,20(6):499-504.
    [8]LIU SY,BAI M,YANG YL,et al.Study on anti-inflammatory effect of external therapy of Sodium Sulfate[J].China J Tradit Chin Med Pharma,2012,27(2):312-315.(in Chinese)刘绍龑,白明,杨亚蕾,等.芒硝外用抗炎作用研究[J].中华中医药杂志,2012,27(2):312-315.
    [9]LI PC,JIN LH.Clinical efficacy of umbilical compress therapy with Rheum officinale and mirabilite in treatment of cirrhotic ascites:a report of 30 cases[J].J Chin Med Pharm,2010,38(4):82-83.(in Chinese)李丕慈,金林红.大黄、芒硝敷脐治疗肝硬化腹水30例临床观察[J].中医药学报,2010,38(4):82-83.
    [10]ZHU XQ,WU CM,CAO JL.Clinical effect of umbilical compress therapy with mirabilite in treatment of cirrhotic ascites:a report of42 cases[J].Strait Pharm J,2009,21(3):142-143.(in Chinese)朱小区,吴春明,曹家麟.芒硝敷脐治疗肝硬化腹水42例临床观察[J].海峡药学,2009,21(3):142-143.
    [11] XU XM,ZOU BQ,ZHU XQ.Observation and attendance of extenal application of mirabilite on liver cirrhosis patients with ascites[J].Chin Manipul Rehabil Med,2011,53(6):56-57.(in Chinese)徐晓美,邹碧泉,朱小区.芒硝外敷治疗肝硬化腹水的观察及护理[J].按摩与康复医学,2011,53(6):56-57.
    [12]ZOU BQ,XU XM,ZHU XQ.Effects of external application of mirabilite on lipopolysaccharide and its binding protein in patients with cirrhotic ascites[J].Jiangxi J Traditi Chin Med,2009,40(317):49-50.(in Chinese)邹碧泉,徐晓美,朱小区.芒硝外敷对肝硬化腹水脂多糖及其结合蛋白的作用[J].江西中医药,2009,40(317):49-50.
    [13]WANG ZY,LIANG XL,GUO XZ.Clinical effect of external application of Yugong Powder combined with mirabilite to Shenque point in hepatitis B patients with cirrhotic ascites:a report of 34 cases[J].Zhejiang J Tradit Chin Med,2012,47(12):884-885.(in Chinese)王治宇,梁学琳,郭献忠.禹功散合芒硝外敷神阙穴治疗乙型肝炎肝硬化腹水34例[J].浙江中医杂志,2012,47(12):884-885.
    [14]FANG Q,ZHANG XJ.A controlled study of TCM umbilical compress combined with TDP irradiation in treatment of cirrhotic ascites[J].Pract Tradit Chin Intern Med,2013,27(2).(in Chinese)方奇,张鑫杰.中药敷脐联合TDP照射治疗肝硬化腹水对照观察[J].实用中医内科杂志,2013,27(2).
    [15]YAO WF.Clinical effect of integrated traditional Chinese and Western medicine therapy for cirrhotic ascites:a report of 60 cases[J].J Emerg Tradit Chin Med,2012,21(8):1358-1359.(in Chinese)姚渭芬.中西医结合治疗肝硬化腹水60例[J].中国中医急症,2012,21(8):1358-1359.
    [16]LI ZX,SHENG JS,SHENG TJ.Clinical effect of integrated traditional Chinese and Western medicine therapy for cirrhotic ascites[J].China Prac Med,2014,9(3):176-177.(in Chinese)李之兴,盛基山,盛天娇.肝硬化腹水应用中西医结合治疗的临床研究[J].中国实用医药,2014,9(3):176-177.
    [17]YANG XZ,HAN LB,SHEN ML.Clinical effect of integrated traditional Chinese and Western medicine therapy for intractable ascites in patients with liver cirrhosis[J].Chin Hepatol,2013,18(8):584-585.(in Chinese)杨秀珍,韩立彬,沈美龙.中西医结合治疗肝硬化难治性腹水疗效观察[J].肝脏,2013,18(8):584-585.
    [18]WU YB,WANG XF.Clinical effect of navel paste therapy with octreotide plus traditional Chinese medicines in treatment of intractable ascites:a report of 64 cases[J].Jiangsu J Traditi Chin Med,2013,45(5):60-61.(in Chinese)吴永斌,王修锋.奥曲肽联合中药脐贴治疗难治性腹水64例临床观察[J].江苏中医药,2013,45(5):60-61.
    [19]BAI LD,ZHANG JZ.Clinical nursing in external application of mirabilite for treating cirrhotic ascites:a report of 25 cases[J].J Qilu Nurs,2009,15(23):57-58.(in Chinese)白联缔,张晋芝.芒硝外敷治疗肝硬化腹水25例临床护理[J].齐鲁护理杂志,2009,15(23):57-58.
    [20]YU HS.Changes in gastrointestinal dynamics in patients with decompensated cirrhosis[J].New Chin Med,1999,30(2):116-117.(in Chinese)于海生.硬化失代偿期患者的胃肠动力学改变[J].新医学,1999,30(2):116-117.
    [21]PAN CF,ZHANG YL,CAI JP,et al.Umbilical compress therapy for cirrhotic ascites[J].Chin J Integr Tradit West Med Liver Dis,2004,14(2):126-128.(in Chinese)潘传芳,张雅丽,蔡俊萍,等.肝硬化腹水的敷脐疗法[J].中西医结合肝病杂志,2004,14(2):126-128.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2091) PDF downloads(481) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return