Research progress in controlled attenuation parameter for assessment of fatty liver disease

Controlled attenuation parameter(CAP) is a noninvasive,quantitative,fast,and reliable novel tool for the assessment of fatty liver disease(FLD),and it has been a hotspot in the noninvasive diagnosis of FLD.This paper introduces factors associated with CAP assessing FLD,the cut-off value for the diagnosis of liver steatosis,and the causes of the failure of CAP measurement and unreliable CAP measurement.The paper believes that even though the noninvasive and quantitative diagnosis of FLD by CAP has been confirmed by many studies,most of the results were obtained with a limited sample size.Therefore,the factors associated with the cut-off value for CAP diagnosing liver steatosis and factors influencing the measurement results still need validation with larger samples and multi-centered research reports.