Relationship between portal vein pressure and Fibro Scan score in cirrhotic patients with concomitant portal hypertension

Objective To analyze the relationship between portal vein pressure and Fibro Scan score in patients with liver cirrhosis using color Doppler ultrasonography and transient elastography( Fibro Scan). Methods Totally 235 patients with liver cirrhosis were selected from the Second People's Hospital of Zhongshan,Guangdong Province,China,from March 2012 to March 2014,with 100 healthy individuals as controls. Color Doppler ultrasonography was performed to measure the portal vein diameter( PVD),mean portal vein velocity( PVVmean),and blood flow quantity of portal vein( PVQ). Portal vein pressure( Ppv) was calculated from the equation of Ppv = 1. 895 1 + 0. 001 1PVQ.Fibro Scan was also performed. Continuous data were expressed as the mean ± standard deviation. Group comparisons were performed by t test. The relationship between test parameters and Ppv was examined by correlation analysis. Results The PVD,PVQ,PVVmean,Ppv,and Fibro Scan score of cirrhotic patients with concomitant portal hypertension were 1. 42 ± 0. 12 cm,1238 ± 145. 23 ml / min,13. 25 ± 1. 56 cm / s,3. 28 ± 0. 17 k Pa,and 27. 81 ± 7. 52 k Pa,respectively,all of which were significantly higher than those in the control group( P <0. 05). Fibro Scan score and PVQ were positively correlated with Ppv in cirrhotic patients( r = 0. 52,P < 0. 001; r = 0. 61,P < 0. 001).Conclusion Fibro Scan score can be used as a reference indicator for noninvasive evaluation of portal hypertension.