Hepatic fibrosis is the common outcome of chronic liver diseases of various causes. At present,liver biopsy is the “gold standard”for the diagnosis of liver fibrosis,but it has limitations and is invasive,which leads to the development of noninvasive assessment of liver fibrosis. The article mainly introduces the technology and application of noninvasive diagnosis of liver fibrosis from the aspects of clinical manifestation,serology,and radiology. It has pointed out the clinical value of these noninvasive diagnosis techniques,and it discusses the progress in clinical research and its limitations for noninvasive diagnosis of liver fibrosis.
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