中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 10
Oct.  2014
Turn off MathJax
Article Contents

The definition and natural history of severe exacerbation of hepatitis B

DOI: 10.3969/j.issn.1001-5256.2014.10.001
  • Received Date: 2014-09-01
  • Published Date: 2014-10-20
  • Despite different opinions on its definition and classification in the past, a consensus has gradually been reached regarding the naming, classification, and clinical diagnosis of liver failure. The classification of liver failure is described, and the definition and natural history of severe exacerbation of hepatitis B are summarized. Antiviral treatment and artificial liver support in the early stage are beneficial for clinical outcomes and prognosis.

     

  • loading
  • [1] NING Q, CHEN Z, WANG YM.Acute exacerbation of chronic hepatitis:basic research and clinical management[M].Wuhan:Huazhong University of Science and Technology Press, 2014:1-756. (in Chinese) 宁琴, 陈智, 王宇明.乙型肝炎重症化基础与临床[M].武汉:华中科技大学出版社, 2014:1-756.
    [2]O'GRADY JG, SCHALM SW, WILLIAMS R.Acute liver failure:redefining the syndromes[J].Lancet, 1993, 342 (8866) :273-275.
    [3]BERNUAU J, RUEFF B, BENHAMOU JP.Fulminant and subfulminant liver failure:defnitions and causes[J].Semin Liver Dis, 1986, 6 (2) :97-106.
    [4]GIMSON AE, O'GRADY JG, EDE RJ, et al.Late onset hepatic failure:clinical, serological and histological features[J].Hepatology, 1986, 6 (2) :288-294.
    [5]MAS A, RODS J.Fulminant hepatic failure[J].Lancet, 1997, 349 (9058) :1081-1085.
    [6]BERNAL W, AUZINGER G, DHAWAN A, et al.Acute liver failure[J].Lancet, 2010, 376 (9736) :190-201.
    [7]WANG YM, CHEN YK, GU CH, et al.Reevaluation of the nomenclature and diagnostic criteria in 477 patients with severe hepatitis[J].Chin J Hepatol, 2000, 8 (5) :261-263. (in Chinese) 王宇明, 陈耀凯, 顾长海, 等.重型肝炎命名和诊断分型的再认识——附477例临床分析[J].中华肝脏病杂志, 2000, 8 (5) :261-263.
    [8]POLSON J, LEE WM.American Association for the Study of Liver Disease.AASLD position paper:the management of acute liver failure[J].Hepatology, 2005, 41 (5) :1179-1197.
    [9]Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases.Chinese Medical Association;Severe Liver Diseases and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association.Diagnostic and treatment guidelines for liver failure[J].Chin J Hepatol, 2006, 14 (9) :643-646. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组、中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊疗指南[J].中华肝脏病杂志, 2006, 14 (9) :643-646.
    [10]LEE WM, SQUIRES RH JR, NYBERG SL, et al.Acute liver failure:summary of a workshop[J].Hepatology, 2008, 47 (4) :1401-1415.
    [11]LARSON AM.Diagnosis and management of acute liver failure[J].Curr Opin Gastroenterol, 2010, 26 (3) :214-221
    [12]SARIN SK, KUMAR A, ALMEIDA JA, et al.Acute-on-chronic liver failure:consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) [J].Hepatol Int, 2009, 3 (1) :269-282.
    [13]LI LJ.Artificial liver[M].Zhejiang:Zhejiang University Press, 2012:1-439. (in Chinese) 李兰娟.人工肝脏[M].浙江:浙江大学出版社, 2012:1-439.
    [14]LIU C, WANG YM, FAN K.Epidemiological and clinical features of hepatitis B virus related liver failure in China[J].World J Gastroenterol, 2011, 17 (25) :3054-3059.
    [15]KE WM, LI XJ, YU LN, et al.Etiological investigation of fatal liver failure during the course of chronic hepatitis B in south east China[J].J Gastroenterol, 2006, 41 (4) :347-351.
    [16]TANG H, MCLACHLAN A.Transcriptional regulation of hepatitis B virus by nuclear hormone receptor is a critical determinant of viral tropism[J].Pro Natl Acad Sci U S A, 2001, 98 (4) :1841-1846.
    [17]LONG Y, CHEN E, LIU C, et al.The correlation of hepatocyte nuclear factor 4 alpha and 3 beta with hepatitis B virus replication in the liver of chronic hepatitis B patients[J].J Viral Hepat, 2009, 16 (8) :537-546.
    [18]HAN M, YAN W, GUO W, et al.Hepatitis B virus-induced hFGL2 transcription is dependent on c-Ets-2 and MAPK signal pathway[J].J Biol Chem, 2008, 283 (47) :32715-32729.
    [19]RAHIMI RS, ROCKEY DC.Complications and outcomes in chronic liver disease[J].Curr Opin Gastroenterol, 2011, 27 (3) :204-209.
    [20]HEATHCOTE EJ.Demography and Presentation of Chronic Hepatitis B Virus Infection[J].Am J Med, 2008, 121 (12 Suppl) :s3-s11.
    [21]WURSTHORN K, WEDEMEYER H, MANNS MP.Managing HBV in patients with impaired immunity[J].Gut, 2010, 59 (10) :1430-1445.
    [22]AGARWAL M, COTTAM S.Laboratory tests in hepatic failure[J].Anasthesia Inten Care Med, 2009, 10 (7) :326-327.
    [23]OLIVER S, van FLORIAN B, JRGEN KR, et al.Current and Future therapies for chronic HBV-infections[J].Reviews Med Microbiol, 2007, 18:79-88.
    [24]MA K, GUO W, HAN M, et al.Entecavir treatment prevents dis ease progression in hepatitis B virus-related acute-on-chronic liver failure:establishment of a novel logistical regression model[J].Hepatol Int, 2012, 6 (4) :735-743.
    [25] Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association.Guidelines for nonbioartificial liver support system in the treatment of liver failure (2009) [J].Chin J Clin Infect Dis, 2009, 2 (6) :321-325. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组.非生物型人工肝支持系统治疗肝衰竭指南 (2009年版) [J].中华临床感染病杂志, 2009, 2 (6) :321-325.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2245) PDF downloads(799) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return