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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 9
Sep.  2014
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Article Contents

Current status of research on liver innate immunity

DOI: 10.3969/j.issn.1001-5256.2014.09.003
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  • Received Date: 2014-06-18
  • Published Date: 2014-09-20
  • Liver innate immunity plays an important role in the defense against pathogen invasion. The mechanisms of liver innate immunity for defending against pathogen invasion are reviewed, including the special anatomical and physiological characteristics of the liver, the features of innate immune cells in the liver ( liver- settled cells and cells raised from blood circulation) and their function and relationship with each other in pathogen invasion, the process of pathogen identification and effect of liver innate immune cells, and the mechanism of liver immune injury and immune tolerance. Given current research on innate immune cells and innate immune molecules in the liver, further studies should be conducted to understand the connection and difference between liver innate immunity and systemic immunity, thus promoting the diagnosis and treatment of liver diseases and deeper research.

     

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