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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2014
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Article Contents

Recent progress in direct- acting antiviral agents for chronic hepatitis C

DOI: 10.3969/j.issn.1001-5256.2014.06.004
  • Received Date: 2014-01-15
  • Published Date: 2014-06-20
  • The current standard treatment for hepatitis C virus ( HCV) infection is a combination of pegylated interferon ( PEG- IFN) and ribavirin. However, it remains incurable in some patients. In recent years, direct acting antiviral agents ( DAAs) that target specific HCV enzymes in HCV life cycle have been developed rapidly. A combination of PEG- IFN, ribavirin, and DAAs can increase the sustained virological response rate in patients with chronic hepatitis C ( CHC) . For patients who cannot use or tolerate interferon therapy, a combination of various DAAs has good efficacy. Therefore, DAAs bring new hope for the treatment of CHC.

     

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