Dr.  Wen-Xing Ding graduated from Shanghai Medical University (now Fudan University) in China in 1992 in Preventive Medicine, and then obtained a Master degree from Toxicology in 1995 at Shanghai Medical University.  He then got his PhD in Molecular Toxicology in 2001 from National University of Singapore.  Dr. Ding then did his Postdoc training at University of Pittsburgh in 2001 and became a research assistant professor at Department of Pathology in 2006 in University of Pittsburgh. Dr. Ding became an assistant professor as part of a COBRE program in 2009 and then professor of Department of Pharmacology, Toxicology and Therapeutics in 2017 at The University of Kansas Medical Center. The Ding laboratory has been working on the role of autophagy in alcohol and drug-induced liver injury as well as liver tumorigenesis since 2009. The Ding Lab is particularly interested in how autophagy selectively removes cellular damaged/excess organelles such as mitochondria and lipid droplets in hepatocytes.  His research work is currently supported by NIAAA and NIDDK and NIA. Dr. Ding has published more than 170 peer-reviewed papers. His papers have been extensively cited for more than 25000 times and his current H-index is 66. In addition to research, Dr. Ding demonstrated outstanding leadership for service.  He has been a program committee member of ASIP (American Society of Investigative Pathology) since 2014, and successfully organized many symposiums for Experimental Biology (EB) meeting in 2015, 2016, 2018 and 2019. He is also the Basic Science Committee and Research Award Committee of AASLD (American Association for the Studies of Liver Diseases). He is currently the vice-Chair of Hepatotoxicity SIG of AASLD.  Dr. Ding currently is the Section Editor for Autophagy and Associate editor for APSB, and is an editorial board member of Hepatology, Hepatology Communications and American Journal of Pathology.

(Selected from a total of 178, H-index 66, total citations >28500 from Google Scholar) 

a. Ni, H.M., Woolbright, B., Copple, B., Luyendyke, J., Cui, W., Jaeschke, H., and Ding, W.X. (2014) Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy. J of Hepatol. 61(3):617-25. PMCID: PMC4143992.

b. Chao X, Wang S, Zhao K, Li Y, Williams JA, Li T, Chavan H, Krishnamurthy P, He XC, Li L, Ballabio A, Ni HM, Ding WX. (2018) Impaired TFEB-mediated lysosomal biogenesis in acute-on-chronic alcohol induced-liver injury in mice. Gastroenterology. 155(3):865-879. PMCID: PMC6120772.

c. Ding, W.X., Ni, H.M, Waguri, S and Komatsu, M. (2022) Lack of Hepatic Autophagy Promotes Severity of Liver Injury but Not Steatosis. J of Hepatol. 25:S0168-8278(22)00330-0. PMID: 35643205. PMCID: PMICD In Progress.

d. Lack of VMP1 Impairs Hepatic Lipoprotein Secretion and Promotes Nonalcoholic Steatohepatitis (2022). Jiang X, Fulte S, Deng F, Chen S, Xie Y, Chao X, He XC, Zhang Y, Li T, Li F, McCoin C, Morris EM, Thyfault J, Liu W, Li L, Davidson NO, Ding WX, Ni HM. J of Hepatol. 19:S0168-8278(22)00245-8. PMCID: PMC9449865.