Advances in tumor microenvironment and immunotherapy of Cholangiocarcinoma

Shun CHEN; Jun WANG

doi:10.3969/j.issn.1001-5256.2022.10.044

Volume 38 Issue 10

Oct. 2022

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Article Navigation > Journal of Clinical Hepatology > 2022 > 38(10): 2428-2432

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Advances in tumor microenvironment and immunotherapy of Cholangiocarcinoma

DOI: 10.3969/j.issn.1001-5256.2022.10.044

Shun CHEN¹,
Jun WANG^{2
,
,
,}

1.
Depantment of General Surgery, Zhongshan Hospital of Traditional Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Zhongshan, Guangdong 528400, China
2.
Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital, Changsha 410005, China

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Corresponding author: Wang Jun, 13973120355@139.com(ORCID: 0000-0002-1596-8490)
Received Date: 2022-03-08
Accepted Date: 2022-04-24
Published Date: 2022-10-20

Abstract

Abstract

The tumor microenvironment plays an important role in the proliferation, invasion and metastasis of cholangiocarcinoma cells. Complicated functional axis determines cholangiocarcinoma heterogeneity and its malignant potential. Targeting some factors in the tumor microenvironment might help reshape immune system of the tumor microenvironment to enhance natural anti-tumor immune responses. As a consequence, the improved immune environment and enhanced immune function will have great clinical potential in prediction of immune response to immunotherapy and identification of novel therapeutic strategies, which can provide a new potential direction for further investigation of targeted therapy of cholangiocarcinoma.
- Bile Duct Neoplasms,
- Tumor Microenvironment,
- Immunotherapy

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References(52)

References

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Advances in tumor microenvironment and immunotherapy of Cholangiocarcinoma

DOI: 10.3969/j.issn.1001-5256.2022.10.044

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Advances in tumor microenvironment and immunotherapy of Cholangiocarcinoma

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