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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 2
Feb.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(2): 471-476

Research advances in the prevention and treatment of hepatic ischemia-reperfusion injury with traditional Chinese medicine components

DOI: 10.3969/j.issn.1001-5256.2022.02.044
  • 1a.

    Graduate School, Qinghai University, Xining 810016, China

  • 1b.

    Medical College, Qinghai University, Xining 810016, China

  • 2.

    First Department of Rehabilitation, Guangzhou Renai Tianhe Hospital, Guangzhou 510630, China

Research funding:

State Administration of Traditional Chinese Medicine—National Training Program for Innovative Backbone Talents of Traditional Chinese Medicine (Guozhongyiyao Renjiaohan [2019]No.128)

More Information
  • Corresponding author: YU Kexian, ykx0421@163.com
  • Received Date: 2021-07-03
  • Accepted Date: 2021-08-10
  • Published Date: 2022-02-20
    Abstract
  • Hepatic ischemia-reperfusion injury (HIRI) is a very common complication of liver transplantation, liver resection, and shock. At present, many studies have been conducted on HIRI, but there is still a lack of drugs for radical treatment in clinical practice. Many factors, such as related cells, molecular mechanisms and signaling pathways, reactive oxygen species and oxidative stress response, nitric oxide, and mitochondria, mediate the development and progression of HIRI, which leads to the decline of patients' quality of life and even endangers their life safety. Based on the pathogenesis of HIRI and related articles, this article summarizes the research advances in the prevention and treatment of HIRI with traditional Chinese medicine components, so as to provide theoretical support for basic research and clinical research on HIRI.

     

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