Application of transjugular liver biopsy in the diagnosis and treatment of complicated and severe liver diseases

Hua TIAN; Qiang YU; Shaoli YOU; Sa LYU; Shuhong LIU; Bing ZHU

doi:10.3969/j.issn.1001-5256.2021.12.027

Volume 37 Issue 12

Dec. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(12): 2874-2877

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Application of transjugular liver biopsy in the diagnosis and treatment of complicated and severe liver diseases

DOI: 10.3969/j.issn.1001-5256.2021.12.027

a.
Department of Liver Diseases, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China
b.
Department of Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China
c.
Department of Pathology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China

Research funding:

Capital Clinical Characteristic Application Research on Funded Projects (Z151100004015019)

Received Date: 2021-05-24
Accepted Date: 2021-07-05
Published Date: 2021-12-20

Abstract

Abstract

Objective To investigate the application value of transjugular liver biopsy (TJLB) in the diagnosis and treatment of complicated and severe liver diseases. Methods A retrospective analysis was performed for the clinical data of 31 patients who underwent TJLB in The Fifth Medical Center of Chinese PLA General Hospital, including indication for puncture, success rate, and final diagnosis. Results Among the 31 patients, there were 15 male patients and 16 female patients. Percutaneous liver biopsy was unsuitable for 8 patients with liver failure and disturbances of blood coagulation, 13 with liver cirrhosis and ascites, and 10 with liver cirrhosis and thrombocytopenia (< 50×10⁹/L), which were the indications for TJLB. The success rate of TJLB puncture was 100%, with 2-4 passes for puncture. No serious adverse event was observed. Of all 31 patients, 26 (83.87%) had a definite diagnosis at discharge, among whom there were 5 patients with idiopathic portal hypertension, 9 patients with drug-induced liver failure or liver cirrhosis, 5 patients with autoimmune liver disease, and 7 patients with liver cirrhosis or liver failure due to other causes, and 5 patients had unknown etiology. In addition, 3 patients underwent biopsy to confirm the diagnosis and decision of whether liver transplantation should be performed. Conclusion TJLB plays an important role in the diagnosis and treatment of complicated and severe liver diseases and still has certain limitations, and therefore, suitable patients should be selected in clinical practice.
- Liver Diseases,
- Biopsy, Needle,
- Diagnosis,
- Therapeutics

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Application of transjugular liver biopsy in the diagnosis and treatment of complicated and severe liver diseases

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Application of transjugular liver biopsy in the diagnosis and treatment of complicated and severe liver diseases

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