Mechanism of action of forkhead box transcription factors in hepatocellular carcinoma and their prospects as treatment targets

Tianyu LI; Huimin YAN

doi:10.3969/j.issn.1001-5256.2021.04.044

Volume 37 Issue 4

Apr. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(4): 931-934

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Mechanism of action of forkhead box transcription factors in hepatocellular carcinoma and their prospects as treatment targets

DOI: 10.3969/j.issn.1001-5256.2021.04.044

Tianyu LI¹,
Huimin YAN^{1, 2
,
,}

1.
Department of Epidemiology and Health Statistics, School of Public Health, Hebei Medical University, Shijiazhuang 050017, China
2.
Clinical Research Center, Shijiazhuang Fifth Hospital, Shijiazhuang 050021, China

Received Date: 2020-09-18
Accepted Date: 2020-11-05
Published Date: 2021-04-20

Abstract

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignant cancers and has high incidence and mortality rates and poor prognosis. Forkhead box (FOX) transcription factor family can regulate cell growth, differentiation, and tissue development and plays an important role in tumor. This article reviews the association of the molecular expression of the FOX family with the development, progression, and prognosis of HCC and analyzes the mechanism of action of FOX in the progression of HCC. It is pointed out that FOX family is expected to become a new target for HCC treatment.
- Carcinoma, Hepatocellular,
- Forkhead Transcription Factors,
- Oncogenes,
- Genes, Tumor Suppressor

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References(45)

References

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Mechanism of action of forkhead box transcription factors in hepatocellular carcinoma and their prospects as treatment targets

DOI: 10.3969/j.issn.1001-5256.2021.04.044

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Mechanism of action of forkhead box transcription factors in hepatocellular carcinoma and their prospects as treatment targets

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