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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 4
Apr.  2020
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Article Contents

Role of hepatic macrophages in the development and progression of primary biliary cholangitis

DOI: 10.3969/j.issn.1001-5256.2020.04.051
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  • Published Date: 2020-04-20
  • Primary biliary cholangitis( PBC) is a chronic autoimmune liver disease characterized by cholestasis and has unknown etiology.Its specific pathogenesis remains unclear,but hepatic macrophages are one of the key aspects of the immune and inflammatory response of PBC and the injury of biliary epithelial cells. Hepatic macrophages are classified into resident Kupffer cells and monocyte-derived macrophages according to their source,and these cells play an important role in the development and progression of PBC. This article reviews the role of hepatic macrophages in the development and progression of PBC.

     

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