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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 1
Jan.  2020
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Article Contents

Research advances in persistent hepatitis B virus infection and its mechanism

DOI: 10.3969/j.issn.1001-5256.2020.01.041
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  • Received Date: 2019-07-28
  • Published Date: 2020-01-20
  • Hepatitis B virus(HBV) belongs to the Hepadnaviridae family and can cause acute and chronic hepatitis,liver cirrhosis,and even liver cancer in humans. Current antiviral drugs cannot completely eliminate HBV in liver cells and thus it is difficult to achieve a curative effect. In recent years,the mechanism of persistent HBV infection has attracted wide attention,which mainly involves host and virus. This article elaborates on the research advances in persistent HBV infection from the aspect of virus,including covalently closed circular DNA,HBV particles,and HBV components.

     

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