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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 10
Oct.  2019
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Article Contents

Role of NLRP3 inflammasome in the development and progression of liver diseases

DOI: 10.3969/j.issn.1001-5256.2019.10.048
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  • Received Date: 2019-05-20
  • Published Date: 2019-10-20
  • Immune cascade due to inflammasome has become a research hotspot in recent years,and the role of NLRP3 inflammasome in the development and progression of liver diseases has attracted more and more attention. This article analyzes the action characteristics and regulatory mechanism of NLRP3 inflammasome in liver diseases,such as viral hepatitis,liver fibrosis,nonalcoholic fatty liver disease,liver failure,and liver cancer,and establishes targeted therapy based on NLRP3 inflammasome to regulate immune response triggered by inflammasome,in order to provide new ideas for the prevention and treatment of liver diseases.

     

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