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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 9
Sep.  2019
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Article Contents

Research advances in the role of gut microbiota in liver diseases

DOI: 10.3969/j.issn.1001-5256.2019.09.053
  • Received Date: 2019-04-17
  • Published Date: 2019-09-20
  • Intestinal dysbacteriosis is an important pathogenic factor for liver diseases. There exists a gut-liver axis between the gut and the liver, which helps with the interactions between these two organs. The liver is an important immune organ, and after being exposed to intestinal bacteria and their metabolites via the portal vein, the liver may activate innate immunity and adaptive immunity, which may lead to liver injury. As an important component of the gut-liver axis, gut microbiota is not only a triggering factor but also a potential therapeutic target for liver diseases. This article elaborates on the association between gut microbiota and liver diseases and points out that in-depth studies should be performed to explore the mechanism of action of gut microbiota and their metabolites in liver disease and further clarify the physiopathological role of gut-liver axis, in order to provide a basis for the prevention and treatment of liver diseases.

     

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