中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 9
Sep.  2019
Turn off MathJax
Article Contents

Further strengthen the clinical and basic research on liver failure

DOI: 10.3969/j.issn.1001-5256.2019.09.001
Research funding:

 

  • Received Date: 2019-05-29
  • Published Date: 2019-09-20
  • Liver failure is a severe clinical syndrome of liver disease with high mortality. Although great achievements have been made in the research on liver failure in recent years, there are still controversies over many issues including the classification, diagnostic criteria, and treatment of liver failure. The pathogenesis of liver failure needs to be further clarified, and innovative strategies for diagnosis and treatment need to be further explored. Therefore, the clinical and basic research on liver failure should be further strengthened to improve the comprehensive diagnosis and treatment level of liver failure and continuously reduce the mortality rate of liver failure.

     

  • loading
  • [1] Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association; Severe Liver Disease and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association. Guideline for diagnosis and treatment of liver failure (2018) [J]. J Clin Hepatol, 2019, 35 (1) :38-44. (in Chinese) 中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊治指南 (2018年版) [J].临床肝胆病杂志, 2019, 35 (1) :38-44.
    [2] TANDON BN, BERNAUAU J, O’GRADY J, et al. Recommendations of the international association for the study of the liver subcommittee on nomenclature of acute and subacute liver failure[J]. J Gastroenterol Hepatol, 1999, 14 (5) :403-404.
    [3] European Association for the Study of the Liver. EASL clinical practical guidelines on the management of acute (fulminant) liver failure[J]. J Hepatol, 2017, 66 (5) :1047-1081.
    [4] ZHANG Q, LI Y, HAN T, et al. Comparison of current diagnostic criteria for acute-on-chronic liver failure[J]. PLo S One, 2015, 10 (3) :e0122158.
    [5] MAHMUD N, KAPLAN DE, TADDEI TH, et al. Incidence and mortality of acute on chronic liver failure using two definitions in patients with compensated cirrhosis[J]. Hepatology, 2019, 69 (5) :2150-2163.
    [6] LEAO GS, LUNARDA FL, PICON RV, et al. Acute-on-chronic liver failure:A comparison of three different diagnostic criteria[J]. Ann Hepatol, 2019, 18 (2) :373-378.
    [7] JALAN R, YURDAYDIN C, BAJAJ JS, et al. Toward an improved definition of acute-on-chronic liver failure[J]. Gastroenterology, 2014, 147 (1) :4-10.
    [8] WU T, LI J, SHAO L, et al. Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure[J]. Gut, 2018, 67 (12) :2181-2191.
    [9] BAJAJ JS, MOREAU R, KAMATH PS, et al. Acute-onchronic liver failure:Getting ready for prime time?[J]. Hepatology, 2018, 68 (4) :1621-1632.
    [10] JORGENSEN I, RAYAMAJHI M, MIAO EA. Programmed cell death as a defence against infection[J]. Nat Rev Immunol, 2017, 17 (3) :151-164.
    [11] TRIANTAFYLLOU E, WOOLLARD KJ, MCPHAIL MJW, et al.The role of monocytes and macrophages in acute and acuteon-chronic liver failure[J]. Front Immunol, 2018, 9 (12) :2948.
    [12] SINGAL AK, SHAH VH. Current trials and novel therapeutic targets for alcoholic hepatitis[J]. J Hepatol, 2019, 70 (2) :305-313.
    [13] LARSEN FS. Artificial liver support in acute and acute-onchronic liver failure[J]. Curr Opin Crit Care, 2019, 25 (2) :187-191.
    [14] ARROYO V. Acute-on-chronic liver failure in cirrhosis requires expedited decisions for liver transplantation[J]. Gastroenterology, 2019, 156 (5) :1248-1249.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1083) PDF downloads(342) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return