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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 7
Jul.  2019
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Article Contents

Clinical value of albumin-bilirubin grade in evaluating the prognosis of hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2019.07.040
  • Received Date: 2019-01-02
  • Published Date: 2019-07-20
  • Hepatocellular carcinoma ( HCC) is one of the most common primary malignant tumors in the world, and although there are various therapeutic methods for HCC, its prognosis remains unsatisfactory. Albumin-bilirubin ( ALBI) grade is a new clinical index which can be used to evaluate liver function and prognosis of patients with HCC. This article reviews the advances in the application of ALBI grade in surgical treatment, local ablation, transarterial chemoembolization, and drug therapy for HCC. It is pointed out that ALBI grade has a good value in predicting the prognosis of HCC patients undergoing different therapies.

     

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  • [1]TORRE LA, BRAY F, SIEGEL RL, et al.Global cancer statistics, 2012[J].CA Cancer J Clin, 2015, 65 (2) :87-108.
    [2]JOHNSON PJ, BERHANE S, KAGEBAYASHI C, et al.Assessment of liver function in patients with hepatocellular carcinoma:A new evidence-based approach-the ALBI grade[J].J Clin Oncol, 2015, 33 (6) :550-558.
    [3]WANG YY, ZHONG JH, SU ZY, et al.Albumin-bilirubin versus Child-Pugh score as a predictor of outcome after liver resection for hepatocellular carcinoma[J].Br J Surg, 2016, 103 (6) :725-734.
    [4]HIRAOKA A, KUMADA T, KUDO M, et al.Hepatic function during repeated TACE procedures and prognosis after introducing sorafenib in patients with unresectable hepatocellular carcinoma:Multicenter analysis[J].Dig Dis, 2017, 35 (6) :602-610.
    [5]GUI B, WEINER AA, NOSHER J, et al.Assessment of the albumin-bilirubin (ALBI) grade as a prognostic indicator for hepatocellular carcinoma patients treated with radioembolization[J].Am J Clin Oncol, 2018, 41 (9) :861-866.
    [6]OH IS, SINN DH, KANG TW, et al.Liver function assessment using albumin-bilirubin grade for patients with very earlystage hepatocellular carcinoma treated with radiofrequency ablation[J].Dig Dis Sci, 2017, 62 (11) :3235-3242.
    [7]NA SK, YIM SY, SUH SJ, et al.ALBI versus Child-Pugh grading systems for liver function in patients with hepatocellular carcinoma[J].J Surg Oncol, 2018, 117 (5) :912-921.
    [8]CHAN AW, CHONG CC, MO FK, et al.Incorporating albumin-bilirubin grade into the cancer of the liver Italian program system for hepatocellular carcinoma[J].J Gastroenterol Hepatol, 2017, 32 (1) :221-228.
    [9]CHAN AW, KUMADA T, TOYODA H, et al.Integration of albumin-bilirubin (ALBI) score into Barcelona Clinic Liver Cancer (BCLC) system for hepatocellular carcinoma[J].JGastroenterol Hepatol, 2016, 31 (7) :1300-1306.
    [10]MA XL, ZHOU JY, GAO XH, et al.Application of the albumin-bilirubin grade for predicting prognosis after curative resection of patients with early-stage hepatocellular carcinoma[J].Clin Chim Acta, 2016, 462:15-22.
    [11]DONG ZR, ZOU J, SUN D, et al.Preoperative albumin-bilirubin score for postoperative solitary hepatocellular carcinoma within the Milan Criteria and Child-Pugh A cirrhosis[J].JCancer, 2017, 8 (18) :3862-3867.
    [12]HO SY, HSU CY, LIU PH, et al.Albumin-bilirubin (ALBI) grade-based nomogram to predict tumor recurrence in patients with hepatocellular carcinoma[J].Eur J Surg Oncol, 2019, 45 (5) :776-781.
    [13]CHAN AWH, ZHONG J, BERHANE S, et al.Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection[J].J Hepatol, 2018, 69 (6) :1284-1293.
    [14]AMISAKI M, UCHINAKA E, MORIMOTO M, et al.Post-operative albumin-bilirubin grade predicts long-term outcomes among Child-Pugh grade A patients with hepatocellular carcinoma after curative resection[J].Hepatobiliary Pancreat Dis Int, 2018, 17 (6) :502-509.
    [15]LI C, ZHANG XY, PENG W, et al.Postoperative albumin-bilirubin grade change predicts the prognosis of patients with hepatitis B-related hepatocellular carcinoma within the Milan Criteria[J].World J Surg, 2018, 42 (6) :1841-1847.
    [16]RAHBARI NN, GARDEN OJ, PADBURY R, et al.Posthepatectomy liver failure:A definition and grading by the International Study Group of Liver Surgery (ISGLS) [J].Surgery, 2011, 149 (5) :713-724.
    [17]ZOU H, WEN Y, YUAN K, et al.Combining albumin-bilirubin score with future liver remnant predicts post-hepatectomy liver failure in HBV-associated HCC patients[J].Liver Int, 2018, 38 (3) :494-502.
    [18]National Health and Family Planning Commission of the People's Republic of China.Diagnosis, management, and treatment of hepatocellular carcinoma (V2017) [J].J Clin Hepatol, 2017, 33 (8) :1419-1431. (in Chinese) 中华人民共和国国家卫生和计划生育委员会.原发性肝癌诊疗规范 (2017年版) [J].临床肝胆病杂志, 2017, 33 (8) :1419-1431.
    [19]CHOK K, CHAN SC, FUNG JY, et al.Survival outcomes of right-lobe living donor liver transplantation for patients with high Model for End-stage Liver Disease scores[J].Hepatobiliary Pancreat Dis Int, 2013, 12 (3) :256-262.
    [20]ZHANG W, LIU C, TAN Y, et al.Albumin-bilirubin score for predicting post-transplant complications following adult-toadult living donor liver transplantation[J].Ann Transplant, 2018, 23:639-646.
    [21]KAO WY, SU CW, CHIOU YY, et al.Hepatocellular carcinoma:Nomograms based on the albumin-bilirubin grade to assess the outcomes of radiofrequency ablation[J].Radiology, 2017, 285 (2) :670-680.
    [22]OMAGARI K, OHBA K, KADOKAWA Y, et al.Comparison of the grade evaluated by“Liver damage”of Liver Cancer Study Group of Japan and Child-Pugh classification in patients with hepatocellular carcinoma[J].Hepatol Res, 2006, 34 (4) :266-272.
    [23]HIRAOKA A, KUMADA T, HIROOKA M, et al.A better method for assessment of hepatic function in hepatocellular carcinoma patients treated with radiofrequency ablation:Usefulness of albumin-bilirubin grade[J].Hepatol Res, 2018, 48 (3) :e61-e67.
    [24]CHONG CCN, LEE KF, CHU CM, et al.Microwave ablation provides better survival than liver resection for hepatocellular carcinoma in patients with borderline liver function:Application of ALBI score to patient selection[J].HPB, 2018, 20 (6) :546-554.
    [25]HICKEY R, MOULI S, KULIK L, et al.Independent analysis of albumin-bilirubin grade in a 765-patient cohort treated with transarterial locoregional therapy for hepatocellular carcinoma[J].J Vasc Interv Radiol, 2016, 27 (6) :795-802.
    [26]WAKED I, BERHANE S, TOYODA H, et al.Transarterial chemoembolisation of hepatocellular carcinoma:Impact of liver function and vascular invasion[J].Br J Cancer, 2017, 116 (4) :448-454.
    [27]MOHAMMED MAA, KHALAF MH, LIANG T, et al.Albuminbilirubin score:An accurate predictor of hepatic decompensation in high-risk patients undergoing transarterial chemoembolization for hepatocellular carcinoma[J].J Vasc Interv Radiol, 2018, 29 (11) :1527-1534.
    [28]OGASAWARA S, CHIBA T, OOKA Y, et al.Liver function assessment according to the Albumin-Bilirubin (ALBI) grade in sorafenib-treated patients with advanced hepatocellular carcinoma[J].Invest New Drugs, 2015, 33 (6) :1257-1262.
    [29]KUO YH, WANG JH, HUNG CH, et al.Albumin-Bilirubin grade predicts prognosis of HCC patients with sorafenib use[J].J Gastroenterol Hepatol, 2017, 32 (12) :1975-1981.
    [30]KYROCHRISTOS ID, ZIOGAS DE, ROUKOS DH.Regorafenib:Anewly approved drug for advanced hepatocellular carcinoma[J].Future Oncol, 2017, 13 (19) :1665-1668.
    [31]LEE PC, CHEN YT, CHAO Y, et al.Validation of the albuminbilirubin grade-based integrated model as a predictor for sorafenib-failed hepatocellular carcinoma[J].Liver Int, 2018, 38 (2) :321-330.
    [32]YUKIMOTO A, HIROOKA M, HIRAOKA A, et al.Using ALBIscore at the start of sorafenib treatment to predict regorafenib treatment candidates in patients with hepatocellular carcinoma[J].Jpn J Clin Oncol, 2019, 49 (1) :42-47.
    [33]SHAO L, SHI YX, ZHU HX, et al.Clinical effect of stereotactic body radiotherapy combined with Kanglaite injection in treatment of primary liver cancer[J].Chin J Med Offic, 2017, 45 (3) :313-315. (in Chinese) 邵亮, 施艳新, 朱慧心, 等.立体定向放射治疗联合康莱特注射液治疗原发性肝癌临床研究[J].临床军医杂志, 2017, 45 (3) :313-315.
    [34]PAN CC, KAVANAGH BD, DAWSON LA, et al.Radiationassociated liver injury[J].Int J Radiat Oncol Biol Phys, 2010, 76 (3 Suppl) :s94-s100.
    [35]LO CH, LIU MY, LEE MS, et al.Comparison between ChildTurcotte-Pugh and albumin-bilirubin scores in assessing the prognosis of hepatocellular carcinoma after stereotactic ablative radiation therapy[J].Int J Radiat Oncol Biol Phys, 2017, 99 (1) :145-152.
    [36]GKIKA E, BETTINGER D, KRAFFT L, et al.The role of albumin-bilirubin grade and inflammation-based index in patients with hepatocellular carcinoma treated with stereotactic body radiotherapy[J].Strahlenther Onkol, 2018, 194 (5) :403-413.
    [37]MURRAY LJ, SYKES J, BRIERLEY J, et al.Baseline albumin-bilirubin (ALBI) score in western patients with hepatocellular carcinoma treated with stereotactic body radiation therapy (SBRT) [J].Int J Radiat Oncol Biol Phys, 2018, 101 (4) :900-909.
    [38]HO CHM, CHIANG CL, LEE FAS, et al.Comparison of platelet-albumin-bilirubin (PALBI) , albumin-bilirubin (ALBI) , and Child-Pugh (CP) score for predicting of survival in advanced HCC patients receiving radiotherapy (RT) [J].Oncotarget, 2018, 9 (48) :28818-28829.
    [39]Nivolumab approved for liver cancer[J].Cancer Discov, 2017, 7 (11) :OF3.
    [40]HARIMOTO N, YOSHIZUMI T, SAKATA K, et al.Prognostic significance of combined albumin-bilirubin and tumor-node-metastasis staging system in patients who underwent hepatic resection for hepatocellular carcinoma[J].Hepatol Res, 2017, 47 (12) :1289-1298.
    [41]COUSSENS LM, WERB Z.Inflammation and cancer[J].Nature, 2002, 420 (6917) :860-867.
    [42]LI C, ZHANG XY, PENG W, et al.Preoperative albumin-bilirubin grade plus platelet-to-lymphocyte ratio predict the outcomes of patients with BCLC stage A hepatocellular carcinoma after liver resection[J].Medicine (Baltimore) , 2018, 97 (29) :e11599.
    [43]LIU PH, HSU CY, HSIA CY, et al.ALBI and PALBI grade predict survival for HCC across treatment modalities and BCLCstages in the MELD Era[J].J Gastroenterol Hepatol, 2017, 32 (4) :879-886.
    [44]MAI RY, YE JZ, WANG YY, et al.Value of albumin-bilirubin score combined with aspartate aminotransferase-to-platelet ratio index in predicting the development of posthepatectomy liver failure in patients with HBV-related hepatocellular carcinoma[J].J Clin Hepatol, 2018, 34 (2) :292-297. (in Chinese) 麦荣云, 叶甲舟, 王言焱, 等.ALBI联合APRI对HBV相关肝细胞癌肝切除术后肝衰竭发生的预测价值[J].临床肝胆病杂志, 2018, 34 (2) :292-297.
    [45] FAN J, SHI YH, TIAN YX.Prevention and treatment strategies of postoperative tumor recurrence after liver transplantation for hepatocellular carcinoma[J].Chin J Dig Surg, 2019, 18 (1) :20-23. (in Chinese) 樊嘉, 史颖弘, 田盂鑫.肝癌肝移植术后肿瘤复发的防治策略[J].中华消化外科杂志, 2019, 18 (1) :20-23.
    [46]LIU YS.Role of modified albumin-vilirubin (ALBI) grade for evaluation of liver function and prognoses of patients with hepatocellular carcinoma[D].Fuzhou:Fujian Medical University, 2016. (in Chinese) 刘有顺.改良的ALBI分级在评估肝细胞癌患者肝功能及其预后中的作用[D].福州:福建医科大学, 2016.
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