Influence of pregnancy on the natural history of chronic hepatitis B virus infection

Chen YuXin; Huang Rui; Wu Chao

doi:10.3969/j.issn.1001-5256.2019.07.004

Volume 35 Issue 7

Jul. 2019

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Article Navigation > Journal of Clinical Hepatology > 2019 > 35(7): 1430-1434

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Influence of pregnancy on the natural history of chronic hepatitis B virus infection

DOI: 10.3969/j.issn.1001-5256.2019.07.004

Department of Infectious Diseases, Affiliated Drum Tower Hospital of Nanjing University Medical School

Received Date: 2019-05-07
Published Date: 2019-07-20

Abstract

Abstract

Chronic hepatitis B virus ( HBV) infection is still a serious public health problem in China, and the HBsAg carrying rate reaches6. 0%-7. 8% in pregnant women. Maternal immune system is suppressed during pregnancy, which may affect the natural history of HBV infection. At present, no consensus has been reached on the influence of pregnancy on the natural history of HBV infection. The article reviews the research advances in the influence of pregnancy on the natural history of HBV infection from the aspects of maternal immunosuppression during pregnancy and the effect of pregnancy on viral replication, HBeAg seroconversion, liver function, and liver disease progression. Pregnant women with chronic HBV infection should be closely monitored in clinical practice in terms of virological examination and liver function examination during pregnancy and postpartum.
- hepatitis B virus,
- pregnancy,
- therapeutics,
- pregnant women

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References(40)

References

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Influence of pregnancy on the natural history of chronic hepatitis B virus infection

DOI: 10.3969/j.issn.1001-5256.2019.07.004

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Influence of pregnancy on the natural history of chronic hepatitis B virus infection

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