中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 3
Mar.  2019
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Article Contents

Research advances in epidemiology, pathogenesis, and diagnosis and treatment of hepatitis D virus infection

DOI: 10.3969/j.issn.1001-5256.2019.03.040
  • Received Date: 2018-09-18
  • Published Date: 2019-03-20
  • Hepatitis B virus ( HBV) /hepatitis D virus ( HDV) co-infection can accelerate the progression of liver diseases, but due to thelimitations of the detection methods for HDV RNA, the epidemiology of HDV remains unclear. Further studies are needed to investigate thepathogenesis of HBV/HDV co-infection caused by HDV and related treatment methods. By reviewing the epidemiological features of HDV, HDV-specific immunity, genotype, and pathogenesis in China and other countries and summarizing HDV detection methods and treatmentmethods, this article shows that current detection methods for HDV infection have low sensitivity and specificity, with a lack of standardizeddetection methods. Exploration of new HDV detection methods will help to develop new and effective anti-HDV drugs, which has great sig-nificance in improving the outcome of HDV infection.

     

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