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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2018
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Article Contents

Association of Th17 cells, regulatory T cells, and their imbalance with nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2018.06.046
  • Received Date: 2017-12-28
  • Published Date: 2018-06-20
  • Nonalcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and genetic susceptibility and is one of the chronic liver diseases that threaten human health. Under certain conditions, Th17 cells and regulatory T (Treg) cells can be transformed to each other to maintain immune homeostasis. In recent years, more and more studies have been performed on the involvement of Th17 and Treg cells in the development and progression of liver diseases. Th17 cells, Treg cells, and their balance may become the new targets for the treatment of NAFLD. This article reviews the latest research advances in the association of Th17 and Treg cells with NAFLD and the role of Th17/Treg balance in the development and progression of NAFLD.

     

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