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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 10
Oct.  2017
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Article Contents

Association between enterohepatic circulation of bile acid and cholestatic liver disease

DOI: 10.3969/j.issn.1001-5256.2017.10.014
  • Received Date: 2017-06-28
  • Published Date: 2017-10-20
  • The development of cholestatic liver disease is closely associated with the enterohepatic circulation disorder of bile acid. This article elaborates on metabolism of bile acid, enterohepatic circulation-related mechanism of hereditary cholestasis, molecular regulation of related transporters, and association between current therapeutic regimens and enterohepatic circulation, in order to investigate the pathogenesis of cholestatic liver disease and provide a basis for the research on new drugs or therapies.

     

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