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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2017
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Advances in pharmacotherapy for primary biliary cholangitis

DOI: 10.3969/j.issn.1001-5256.2017.06.037
  • Received Date: 2017-02-27
  • Published Date: 2017-06-20
  • The pathogenesis of primary biliary cholangitis (PBC) remains unclear. Ursodeoxycholic acid (UDCA) is currently the only drug approved by the Food and Drug Administration for the treatment of PBC, but some patients have a poor response to UDCA. New therapies can be considered for these patients. This article reviews the advances in drugs for PBC, including 6α-ethyl-chenodeoxycholic acid, fibrates, budesonide, and biological agents, and points out that these drugs bring new hope for PBC patients, but large-scale clinical studies are needed to confirm the long-term efficacy and safety.

     

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