中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 11
Nov.  2016
Turn off MathJax
Article Contents

Research advances in diagnosis and treatment of liver disease during pregnancy

DOI: 10.3969/j.issn.1001-5256.2016.11.049
  • Published Date: 2016-11-20
  • Liver disease during pregnancy is classified as pregnancy- specific liver disease and non- pregnancy- specific liver disease. The unique physicochemical status during pregnancy increases the burden of liver metabolism. Once liver injury occurs,it tends to be more serious and is closely associated with maternal and fetal outcome. If no diagnosis and treatment are given in time,pregnant women and parturients may experience more complications and the mortality rate of perinatal infants will also increase. This article reviews the latest research advances in the diagnosis and treatment of liver disease during pregnancy,in order to provide a reference for the diagnosis and treatment of liver disease during pregnancy in clinical practice.

     

  • loading
  • [1]JOSHI D,JAMES A,QUAGLIA A,et al.Liver disease in pregnancy[J].Lancet,2010,375(9714):594-605.
    [2]KAMIMURA K,ABE H,KAWAI H,et al.Advances in understanding and treating liver diseases during pregnancy:a review[J].World J Gastroenterol,2015,21(17):5183-5190.
    [3]MARSCHALL HU,WIKSTRM SHEMER E,LUDVIGSSON JF,et al.Intrahepatic cholestasis of pregnancy and associated hepatobiliary disease:a population-based cohort study[J].Hepatology,2013,58(4):1385-1391.
    [4]XIAO L,ZHENG JL.Research advances in poor pregnancy outcome caused by intrahepatic cholestasis of pregnancy[J].Clin J Med Offic,2015,43(10):1098-1100.(in Chinese)肖丽,郑剑兰.妊娠期肝内胆汁淤积症不良妊娠结局的研究进展[J].临床军医杂志,2015,43(10):1098-1100.
    [5]CHAPPELL LC,GURUNG V,SEED PT,et al.Ursodeoxycholic acid versus placebo,and early term delivery versus expectant management,in women with intrahepatic cholestasis of pregnancy:semifactorial randomised clinical trial[J].BMJ,2012,344:e3799.
    [6]BACQ Y,SENTILHES L,REYES HB,et al.Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy:a meta-analysis[J].Gastroenterology,2012,143(6):1492-1501.
    [7]GLANTZ A,MARSCHALL HU,LAMMERT F,et al.Intrahepatic cholestasis of pregnancy:a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid[J].Hepatology,2005,42(6):1399-1405.
    [8]TRAN TT,AHN J,REAU NS.ACG clinical guideline:liver disease and pregnancy[J].Am J Gastroenterol,2016,111(2):176-194.
    [9]CH'NG CL,MORGAN M,HAINSWORTH I,et al.Prospective study of liver dysfunction in pregnancy in Southwest Wales[J].Gut,2002,51(6):876-880.
    [10]SIBAI BM.Diagnosis and management of gestational hypertension and preeclampsia[J].Obstet Gynecol,2003,102(1):181-192.
    [11]DUCKITT K,HARRINGTON D.Risk factors for pre-eclampsia at antenatal booking:systematic review of controlled studies[J].BMJ,2005,330(7491):565.
    [12]LO JO,MISSION JF,CAUGHEY AB.Hypertensive disease of pregnancy and maternal mortality[J].Curr Opin Obstet Gynecol,2013,25(2):124-132.
    [13]American College of Obstetricians and Gynecologists;Task Force on Hypertension in Pregnancy.Report of the american college of obstetricians and gynecologists'task force on hypertension in pregnancy[J].Obstet Gynecol,2013,122(5):1122-1131.
    [14]SIBAI BM.Etiology and management of postpartum hypertension-preeclampsia[J].Am J Obstet Gynecol,2012,206(6):470-475.
    [15]WEINSTEIN L.Syndrome of hemolysis,elevated liver enzymes,and low platelet count:a severe consequence of hypertension in pregnancy[J].Am J Obstet Gynecol,1982,142(2):159-167.
    [16]ABILDGAARD U,HEIMDAL K.Pathogenesis of the syndrome of hemolysis,elevated liver enzymes,and low platelet count(HELLP):a review[J].Eur J Obstet Gynecol Reprod Biol,2013,166(2):117-123.
    [17]GOEL A,JAMWAL KD,RAMACHANDRAN A,et al.Pregnancy-related liver disorders[J].J Clin Exp Hepatol,2014,4(2):151-162.
    [18]KNIGHT M,NELSON-PIERCY C,KURINCZUK JJ,et al.A prospective national study of acute fatty liver of pregnancy in the UK[J].Gut,2008,57(7):951-956.
    [19]YANG Z,ZHAO Y,BENNETT MJ,et al.Fetal genotypes and pregnancy outcomes in 35 families with mitochondrial trifunctional protein mutations[J].Am J Obstet Gynecol,2002,187(3):715-720.
    [20]GEENES V,WILLIAMSON C.Liver disease in pregnancy[J].Best Pract Res Clin Obstet Gynaecol,2015,29(5):612-624.
    [21]YU Y,ZHENG HL,MA F,et al.A clinical study of plasma exchange combined with continuous veno-venous hemodiafiltration in acute fatty liver of pregnant with acute liver and renal failure[J].Chin J Med Offic,2016,44(7):670-673.(in Chinese)于艳,郑昊林,马峰,等.妊娠期急性脂肪肝伴急性肝肾功能衰竭[J].临床军医杂志,2016,44(7):670-673.
    [22]SINGH AE,PLITT SS,OSIOWY C,et al.Factors associated with vaccine failure and vertical transmission of hepatitis B among a cohort of Canadian mothers and infants[J].J Viral Hepat,2011,18(7):468-473.
    [23]ZHANG H,PAN CQ,PANG Q,et al.Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-life practice[J].Hepatology,2014,60(2):468-476.
    [24]GREENUP AJ,TAN PK,NGUYEN V,et al.Efficacy and safety of tenofovir disoproxil fumarate in pregnancy to prevent perinatal transmission of hepatitis B virus[J].J Hepatol,2014,61(3):502-507.
    [25]SARKAR M,TERRAULT NA.Ending vertical transmission of hepatitis B:the third trimester intervention[J].Hepatology,2014,60(2):448-451.
    [26]LIU CP,ZENG YL,ZHOU M,et al.Factors associated with mother-to-child transmission of hepatitis B virus despite immunoprophylaxis[J].Intern Med J,2015,54(7):711-716.
    [27]PAN CQ,DUAN Z,DAI E,et al.Tenofovir to prevent hepatitis B transmission in mothers with high viral load[J].N Engl J Med,2016,374(24):2324-2334.
    [28]TAN HH,LUI HF,CHOW WC.Chronic hepatitis B virus(HBV)infection in pregnancy[J].Hepatol Int,2008,2(3):370-375.
    [29]SOOKOIAN S.Effect of pregnancy on pre-existing liver disease:chronic viral hepatitis[J].Ann Hepatol,2006,5(3):190-197.
    [30]ZINKERNAGEL AS,von WYL V,LEDERGERBER B,et al.Eligibility for and outcome of hepatitis C treatment of HIVcoinfected individuals in clinical practice:the Swiss HIV cohort study[J].Antivir Ther,2006,11(2):131-142.
    [31]RUSSELL MA,CRAIGO SD.Cirrhosis and portal hypertension in pregnancy[J].Semin Perinatol,1998,22(2):156-165.
    [32]AGGARWAL N,NEGI N,AGGARWAL A,et al.Pregnancy with portal hypertension[J].J Clin Exp Hepatol,2014,4(2):163-171.
    [33]WESTBROOK RH,YEOMAN AD,KRIESE S,et al.Outcomes of pregnancy in women with autoimmune hepatitis[J].J Autoimmun,2012,38(2-3):j239-j244.
    [34]KHUROO MS,KAMILI S.Aetiology,clinical course and outcome of sporadic acute viral hepatitis in pregnancy[J].J Viral Hepat,2003,10(1):61-69.
    [35]DEVARBHAVI H,KREMERS WK,DIERKHISING R,et al.Pregnancy-associated acute liver disease and acute viral hepatitis:differentiation,course and outcome[J].J Hepatol,2008,49(6):930-935.
    [36]BANAIT VS,SANDUR V,PARIKH F,et al.Outcome of acute liver failure due to acute hepatitis E in pregnant women[J].Indian J Gastroenterol,2007,26(1):6-10.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2106) PDF downloads(497) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return