中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 8
Aug.  2016
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Article Contents

Role of T-helper cell 17 in the development and progression of hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2016.08.046
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  • Received Date: 2016-03-10
  • Published Date: 2016-08-20
  • Hepatocellular carcinoma( HCC) is one of the most common malignant tumors in the world. How to improve cure rate and reduce recurrence and metastasis of HCC have always been hot topics in research. T- helper cell 17( Th17),an important subset of CD4+T-helper cells,plays a critical role in infection,autoimmune response,and tumor microenvironment. This article introduces the discovery of Th17 and related cytokines,summarizes its mechanisms of action and clinical significance in the development and progression of HCC,and provides some clues for new targets in the treatment of HCC and prognosis prediction.

     

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