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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 8
Aug.  2016
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Article Contents

Research advances in treatment of primary biliary cholangitis

DOI: 10.3969/j.issn.1001-5256.2016.08.012
  • Received Date: 2016-04-05
  • Published Date: 2016-08-20
  • Primary biliary cholangitis( PBC) is an autoimmune liver disease mainly involving intrahepatic interlobular bile ducts and can progress to liver fibrosis,cirrhosis,and even liver failure. At present,the only drug approved for the treatment of PBC is ursodeoxycholic acid( UDCA),but up to 40% of PBC patients have suboptimal response to UDCA,and the risk of related complications is increased. Nowadays,other drugs and treatment methods,such as fibrates,glucocorticoids,immunosuppressants,obeticholic acid,biological agents,and mesenchymal stem cells,have been gradually applied in clinical practice and have brought the hope for the treatment of these patients.

     

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