|
[1]YOSHIMOTO S,LOO TM,ATARASHI K,et al.Obesity-induced gu microbial metabolite promotes liver cancer through senescence secretome[J].Nature,2013,499(7456):97-101.
|
|
[2]LEE MY,LIN KD,HSIAO PJ,et al.The association of diabetes mellitus with liver,colon,lung,and prostate cancer is independent of hypertension,hyperlipidemia,and gout in Taiwanese patients[J].Metabolism,2012,61(2):242-249.
|
|
[3]WANG ZS,HOU AM.Analysis on the risk factors of primary hepatic cancer related to viral infections[J].Int J Virol,2015,22(6):399-402.(in Chinese)王智珊,侯安明.病毒感染相关性原发性肝癌患病危险因素分析[J].国际病毒学杂志,2015,22(6):399-402.
|
|
[4]LIANG TT,ZHENG ZJ,QIAO YX.Research advances in association between diabetes and primary liver cancer and related mechanisms[J].Chin J Prevent Med,2014,48(10):921-924.(in Chinese)梁彤彤,郑志杰,乔永霞.糖尿病与原发性肝癌关系及作用机制的研究进展[J].中华预防医学杂志,2014,48(10):921-924.
|
|
[5]ZHANG H,GAO C,FANG L,et al.Metformin and reduced risk of hepatocellular carcinoma in diabetic patients:a met-analysis[J].Scand J Gastroenterol,2013,48(1):78-87.
|
|
[6]CHEN CI,KUAN CF,FANG YA,et al.Cancer risk in HBV patients with statin and metformin use:a population-based cohort study[J].Medicine(Baltimore),2015,94(6):e462.
|
|
[7]OLIVA J,ZHONG J,BUSLON VS,et al.The effect of SAMe and betaine on Hepa 1-6,C34 and E47 liver cell survival in vitro[J].Exp Mol Pathol,2012,92(1):126-130.
|
|
[8]BOSETTI C,FRANCHI M,NICOTRA F,et al.Insulin and other antidiabetic drugs and hepatocellular carcinoma risk:a nested case-control study based on Italian healthcare utilization databases[J].Pharmacoepidemiol Drug Saf,2015,24(7):771-778.
|
|
[9]BHALLA K,HWANG BJ,DEWI RE,et al.Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver diease[J].Liver Int,2010,30(5):750-758.
|
|
[10]McG LYNN KA,HAGBERG K,CHEN J,et al.Statin use and risk of primary liver cancer in the Clinical Practice Research Datalink[J].J Natl Cancer Inst,2015,107(4).pii:djv009.
|
|
[11]BJORKHEM BL,BACKHEDEN M,SODERBERG LK.Statin treatment reduces the risk of hepatocellular carcinoma but not colon cancer-results from a nationwide case-control study in Sweden[J].Pharmacoepidemiol Drug Saf,2014,23(10):1101-1106.
|
|
[12]McG LYNN KA,DIVINE GW,SAHASRABUDDHE VV,et al.Statin use and risk of hepatocellular carcinoma in a U.S.population[J].Cancer Epidemiol,2014,38(5):523-527.
|
|
[13]SHI M,ZHENG H,NIE B,et al.Statin use and risk of liver cancer:an update meta-analysis[J].BMJ Open,2014,4(9):e005399.
|
|
[14]BUTT AA,YAN P,BONILLA H,et al.Effect of addition of statins to antiviral therapy in hepatitis C virus-infected persons:results from ERCHIVES[J].Hepatology,2015,62(2):365-374.
|
|
[15]SHAO JY,LEE FP,CHANG CL,et al.Statin-based palliativetherapy for hepatocellular carcinoma[J].Medicine(Baltimore),2015,94(42):e1801.
|
|
[16]FRAU M,FEO F,PASCALE RM.Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis[J].J Hepatol,2013,59(4):830-841.
|
|
[17]CHUAN C,GE W.Mechanisms of hepatocellular carcinoma and challenges and opportunities for molecular targeted therapy[J].World J Hepatol,2015,7(15):1964-1970.
|
|
[18]LI TW,PENG H,YANG H,et al.S-Adenosylmethionine and methylthioadenosine inhibitβ-catenin signaling by multiple mechanisms in liverand colon cancer[J].Mol Pharmacol,2015,87(1):77-86.
|
|
[19]TOMASI ML,RYOO M,RAMANI K,et al.Methionine adenosyltransferaseα2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells[J].Oncotarget,2015,6(35):37706-37723.
|
|
[20]SEEWOO V,YANG W,DU H,et al.The different induction mechanisms of growth arrest DNA damage inducible gene 45βin human hepatoma cell lines[J].Chemotherapy,2012,58(2):165-174.
|
|
[21]GU JY,XUE T,DING YT.Research advances in rapamycin target protein signaling pathway in malignant liver tumors[J].Chin J Exp Surg,2014,31(10):2349-2350.(in Chinese)顾劲扬,薛恬,丁义涛.雷帕霉素靶蛋白信号通路在肝脏恶性肿瘤中的研究进展[J].中华实验外科杂志,2014,31(10):2349-2350.
|
|
[22]CEREZO M,TOMIC T,BALLOTTI R,et al.Is it time to test biguanide metformin in the treatment of melanoma?[J].Pigment Cel Melanoma Res,2015,28(1):8-20.
|
|
[23]ALBA L,LUCAS BS,MATTHEW GVH.Understanding the complex-I-ty of metformin action:limiting mitochondrial respiration to improve cancer therapy[J].BMC Biology,2014,12(1):82-85.
|
|
[24]OBARA A,FUJITA Y,ABUDUKADIER A,et al.DEPTOR-related mT OR suppression is involved in metformin's anti-cancer action in human liver cancer cells[J].Biochem Biophys Res Commun,2015,460(4):1047-1052.
|
|
[25]LEONE A,Di Gennaro E,BRUAAESE F,et al.New perspective for an old antidiabetic drug:metformin as anticancer agent[J].Cancer Treat Res,2014,159:355-376.
|
|
[26]MIRANDA VC,BARROSO-SOUSA R,GLASBERG J,et al.Exploring the role of metformin in anticancer treatments:a systematic review[J].Drugs Today(Barc),2014,50(9):623-640.
|
|
[27]BHALLA K,HWANG BJ,DEWI RE,et al.Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis[J].Cancer Prev Res(Phila),2012,5(4):544-552.
|
|
[28]CHENG J,HUANG T,LI Y,et al.AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma[J].PLoS One,2014,9(4):e93256.
|
|
[29]QU H,YANG X.Metformin inhibits angiogenesis induced by interaction of hepatocellular carcinoma with hepatic stellate cells[J].Cell Biochem Biophys,2015,71(2):931-936.
|
|
[30]ALGIRE C,MOISEEVA O,DESCHENES-SIMARD X,et al.Metformin reduces endogenous reactive oxygen species and associated DNA damage[J].Cancer Prev Res,2012,5(4):536-543.
|
|
[31]BAO B,WANG Z,ALI S,et al.Metformin inhibits cell proliferation,migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells[J].Cancer Prev Res,2012,5(3):355-364.
|
|
[32]MATUSEWICZ L,MEISSNER J,TOPORKIEWICZ M,et al.The effect of statins on cancer cells-review[J].Tumour Biol,2015,36(7):4889-4904.
|
|
[33]LU M,QIN LX.Research advances in molecular biological mechanisms of metastasis and recurrence of liver cancer[J].J Hepatobiliary Surg,2014,22(4):314-317.(in Chinese)鲁明,钦伦秀.肝癌转移复发机制的分子生物学研究进展[J].肝胆外科杂志,2014,22(4):314-317.
|
|
[34]ACIMOVIC J,LOVGREN-SANDBLOM A,ERIKSSON LC,et al.The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone[J].Biochem Biophys Res Commun,2012,425(2):348-352.
|
|
[35]CAO ZW,FAN-MINOGUE H,BELLOVIN DI,et al.MYC phosphorylation,activation,and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase[J].Cancer Res,2011,71(6):2286-2297.
|
|
[36]SKOGASTIERNA C,JOHANSSON M,PARINI P,et al.Statins inhibit expression of thioredoxin reductase 1 in rat and human liver and reduce tumour development[J].Biochem Biophys Res Commun,2012,417(3):1046-1051.
|
DownLoad: