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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 32 Issue 1
Jan.  2016
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Article Contents

Research progress in anti-HCV therapeutic regimens without interferon

DOI: 10.3969/j.issn.1001-5256.2016.01.037
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  • Received Date: 2015-04-28
  • Published Date: 2016-01-20
  • There are about 150 million people around the world with chronic hepatitis C virus( HCV) infection currently,of whom 20%will ultimately progress to cirrhosis and eventually die of end- stage liver disease and hepatocellular carcinoma. Interferon( IFN) has long been recognized as the cornerstone of the treatment of chronic hepatitis C because of its role in sustained virologic response and prevention of disease progression. However,it has limited efficacy and multiple adverse effects. In recent years,direct- acting antiviral agents( DAAs)have shown good efficacy. This review summarizes the recent advances in IFN- free anti- HCV therapeutic regimens based on DAAs. We believe that,with the emergence of DAAs,IFN- free therapies will develop rapidly and display better prospects.

     

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