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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2014
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Article Contents

Research progress in tumor- associated antigen antibodies for diagnosis of liver cancer

DOI: 10.3969/j.issn.1001-5256.2014.06.025
  • Received Date: 2013-06-29
  • Published Date: 2014-06-20
  • Liver cancer is one of the most common malignant tumors in the world. The mortality of patients with liver cancer remains high even with increasing progress in therapies. Early diagnosis is helpful for prolonging the survival of patients, so new biomarkers need to be explored for timely diagnosis and treatment of liver cancer. The present research focuses on tumor- associated antigens ( TAAs) and their corresponding autoantibodies as serological biomarkers of liver cancer. The production of autoantibodies and the TAAs and anti- TAAs currently found in the liver cancer tissue are summarized. In addition, it is pointed out that these newly found autoantibodies have relatively high sensitivity and specificity for the early diagnosis of liver cancer.

     

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