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Volume 40 Issue 2
Feb.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(2): 391-396

Application of Mendelian randomization in liver cancer

DOI: 10.12449/JCH240228
  • a.

    Department of Gastroenterology，Lequn Branch，The First Hospital of Jilin University，Changchun 130021，China

  • b.

    Department of Emergency Medicine，Lequn Branch，The First Hospital of Jilin University，Changchun 130021，China

Research funding:

Finance Department Project of Jilin Province (JLSWSRCZX2020-049)

More Information
  • Corresponding author: LYU Hao， 309098144@qq.com （ORCID： 0000-0001-6575-4338）
  • Received Date: 2023-05-16
  • Accepted Date: 2023-06-06
  • Published Date: 2024-02-19
    Abstract
  • In recent years， the research method of Mendelian randomization based on genome-wide association studies has been widely used for etiological exploration in the medical field， which can effectively overcome the confounding biases and interference of reverse causalities in traditional observational researches with its unique advantages of the distributive randomness and timing priority of genetic variants. This article reviews the method of Mendelian randomization and its application in liver cancer， in order to provide new ideas for the research on causal association in liver cancer.

     

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