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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 2
Feb.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(2): 225-228

Clinical practice and research advances in artificial liver support therapy

DOI: 10.12449/JCH240201

  • Department of Gastroenterology and Hepatology，Tianjin People’s Hospital，Tianjin Union Medical Center Affiliated to Nankai University，Tianjin 300121，China

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  • Corresponding author: HAN Tao， hantaomd@126.com （ORCID： 0000-0003-4216-6968）
  • Received Date: 2023-11-20
  • Accepted Date: 2023-12-20
  • Published Date: 2024-02-19
    Abstract
  • Artificial liver support system is one of the important therapies for liver failure， and in recent years， the role of non-bioartificial liver support system in the treatment of liver failure has been gradually recognized， with wide application in non-liver failure diseases. In clinical practice， various factors should be considered to reasonably select the timing and mode of non-bioartificial liver support therapy， and standardized， individualized， and precise treatment and optimal combination of different modes are the trend of the clinical application of artificial liver support therapy. There have been constant improvements in the key techniques of bioartificial liver support system such as seed cell source and bioreactor， and some of them have entered the stage of clinical trial. Although remarkable progress has been made in the clinical practice and research of artificial liver support therapy， there are still many challenges， and it is urgently needed to solve the problems of how to further improve its efficacy and safety through technological innovation and combination optimization and how to obtain higher-level evidence-based medical evidence through high-quality clinical trials.

     

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