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肝窦阻塞综合征成功诊治1例报告

耿雯倩 朱浩 杨鑫 李婉玉 许芳 蔡艳俊 高普均

引用本文:
Citation:

肝窦阻塞综合征成功诊治1例报告

DOI: 10.3969/j.issn.1001-5256.2023.02.023
基金项目: 

吉林大学第一医院交叉学科创新项目 (JDYYJC006)

伦理学声明:本例报告已获得患者知情同意。
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:耿雯倩负责课题设计,资料分析,撰写论文;朱浩、杨鑫、许芳、蔡艳俊参与收集数据,修改论文;李婉玉、高普均负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    李婉玉,liwanyu@jlu.edu.cn (ORCID: 0000-0002-0706-7019)

A case report of successful diagnosis and treatment of hepatic sinusoidal obstruction syndrome

Research funding: 

Interdisciplinary Innovation Project of the First Hospital of Jilin University (JDYYJC006)

More Information
  • 图  1  肝胆胰多排CT平扫+三期增强

    注:a、b为治疗前肝内静脉分支显示不清;c、d为治疗后肝内静脉可见显影(白色箭头所示)。

    Figure  1.  Hepatobiliary and pancreatic multi-slice CTplain scan+three-phase enhancement

    图  2  肝穿刺活检结果(HE染色,×200)

    注:a,治疗前肝穿刺活检:肝腺泡结构紊乱,肝小叶中央静脉周围Ⅲ带及Ⅱ带肝窦高度扩张及淤血,Ⅲ带大部分肝细胞萎缩、消失;b,治疗后肝穿刺活检:肝腺泡结构大致维持正常,肝细胞弥漫水样变性,肝窦不规则扩张。

    Figure  2.  Liver biopsy results (HE staining, ×200)

  • [1] REN XF, ZHUGE YZ, CHEN SY, et al. Gynura segetum-related hepatic sinusoidai obstruction syndrome: a national multicenter clinical study[J]. Chin J Dig, 2017, 37(8): 523-529. DOI: 10.3760/cma.j.issn.0254-1432.2017.08.004.

    任晓非, 诸葛宇征, 陈世耀, 等. 土三七相关肝窦阻塞综合征的全国多中心临床调研分析[J]. 中华消化杂志, 2017, 37(8): 523-529. DOI: 10.3760/cma.j.issn.0254-1432.2017.08.004.
    [2] LIU SS, ZHOU XD. Study on gynura segetum-induced hepatic sinusoidal obstruction syndrome[J]. J Clin Intern Med, 2020, 37(4): 256-259. DOI: 10.3969/j.issn.1001-9057. 2020.04.004.

    刘少松, 周晓东. 吡咯烷生物碱诱导肝窦阻塞综合征的研究进展[J]. 临床内科杂志, 2020, 37(4): 256-259. DOI: 10.3969/j.issn.1001-9057. 2020.04.004.
    [3] Cooperative Group for Hepatic and Gall Diseases, Chinese Society of Gastroenterology, Chinese Medical Association. Expert consensus on diagnosis and treatment of pyrrolidine alkaloids-related sinusoidal obstruction syndrome (2017, Nanjing)[J]. J Clin Hepatol, 2017, 33(9): 1627-1637. DOI: 10.3969/j.issn.1001-5256.2017.09.003.

    中华医学会消化病学分会肝胆疾病协作组. 吡咯生物碱相关肝窦阻塞综合征诊断和治疗专家共识意见(2017年, 南京)[J]. 临床肝胆病杂志, 2017, 33(9): 1627-1637. DOI: 10.3969/j.issn.1001-5256.2017.09.003.
    [4] XIAO J, TU J, ZHANG H, et al. Risk factors of poor prognosis in patients with pyrrolidine alkaloid-induced hepatic sinusoidal obstruction syndrome after transjugular intrahepatic portosystemic shunt[J]. Hepatol Int, 2021, 15(3): 720-729. DOI: 10.1007/s12072-020-10126-x.
    [5] WANG JY, GAO H. Tusanqi and hepatic sinusoidal obstruction syndrome[J]. J Dig Dis, 2014, 15(3): 105-107. DOI: 10.1111/1751-2980.12112.
    [6] WANG LL, SUN J. Advances in diagnosis and treatment of hepatic sinus obstruction syndrome caused by pyrrole alkaloids[J]. Int J Dig Dis, 2020, 40(2): 96-99. DOI: 10.3969/j.issn. 1673-534X.2020.02.008.

    王露露, 孙璟. 吡咯生物碱导致的肝窦阻塞综合征的诊治进展[J]. 国际消化病杂志, 2020, 40(2): 96-99. DOI: 10.3969/j.issn. 1673-534X.2020.02.008.
    [7] LIU ZL, FAN ZP, GOU YS. Clinical features, pathogenesis, and diagnosis and treatment of different types of hepatic sinusoidal obstruction syndrome[J]. J Clin Hepatol, 2019, 35(1): 208-212. DOI: 10.3969/j.issn.1001-5256.2019.01.046.

    刘贞利, 范作鹏, 勾钰淞, 等. 不同类型肝窦阻塞综合征的临床特征、发病机制与诊治[J]. 临床肝胆病杂志, 2019, 35(1): 208-212. DOI: 10.3969/j.issn.1001-5256.2019.01.046.
    [8] DIGNAN FL, WYNN RF, HADZIC N, et al. BCSH/BSBMT guideline: diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation[J]. Br J Haematol, 2013, 163(4): 444-457. DOI: 10.1111/bjh.12558.
    [9] MOHTY M, MALARD F, ABECASSIS M, et al. Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives-a position statement from the European Society for Blood and Marrow Transplantation (EBMT)[J]. Bone Marrow Transplant, 2015, 50(6): 781-789. DOI: 10.1038/bmt.2015.52.
    [10] LI SY, WANG Y. Progress in the pathogenesis, clinical diagnosis and treatment of hepatic sinus obstruction syndrome induced by Tuanqi[J]. Chin Hepatol, 2018, 23(6): 540-542. DOI: 10.3969/j.issn.1008-1704.2018.06.027.

    李世英, 汪艳. 土三七致肝窦阻塞综合征的发生机制与临床诊治研究进展[J]. 肝脏, 2018, 23(6): 540-542. DOI: 10.3969/j.issn.1008-1704.2018.06.027.
    [11] LIU Z, JI SL, WANG FS. Research progress of the pharmacological effects and clinical applications of low molecular weight heparins[J]. Pharm Biotech, 2014, 21(6): 573-578. DOI: 10.19526/j.cnki.1005-8915.2014.06.020.
    [12] Branch of Gastrointestinal Diseases, China Association of Chinese Medicine. Expert consensus on TCM diagnosis and treatment of ascites due to cirrhosis (2017)[J]. J Clin Hepatol, 2017, 33(9): 1621-1626. DOI: 10.3969/j.issn.1001-5256.2017.09.002.

    中华中医药学会脾胃病分会. 肝硬化腹水中医诊疗专家共识意见(2017)[J]. 临床肝胆病杂志, 2017, 33(9): 1621-1626. DOI: 10.3969/j.issn.1001-5256.2017.09.002.
    [13] JIANG MJ, SONG LS, XIN GJ, et al. Low-molecular-weight heparin sodium for the treatment of hepatic sinusoidal obstruction syndrome: A case report[J]. J Clin Hepatol, 2019, 35(7): 1594-1595. DOI: 10.3969/j.issn.1001-5256.2019.07.035.

    姜敏杰, 宋立莎, 辛桂杰, 等. 低分子肝素钠治疗肝窦阻塞综合征1例报告[J]. 临床肝胆病杂志, 2019, 35(7): 1594-1595. DOI: 10.3969/j.issn.1001-5256.2019.07.035.
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  • 收稿日期:  2022-06-10
  • 录用日期:  2022-07-25
  • 出版日期:  2023-02-20
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