HDV RNA检测的临床意义与方法

林妍雪; 秦艳丽; 张继明

doi:10.3969/j.issn.1001-5256.2022.12.028

HDV RNA检测的临床意义与方法

DOI: 10.3969/j.issn.1001-5256.2022.12.028

复旦大学附属华山医院感染科，上海市传染病与生物安全应急响应重点实验室，国家传染病医学中心，上海 200040

基金项目:

国家自然科学基金 (81871640);

国家自然科学基金 (82172255)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：林妍雪负责查阅文献和撰写文章；秦艳丽负责修改文章；张继明负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
张继明，jmzhang@fudan.edu.cn

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出版历程
- 收稿日期: 2022-04-25
- 录用日期: 2022-05-26
- 出版日期: 2022-12-20

Clinical significance and methods of hepatitis D virus RNA detection

Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China

Research funding:

National Natural Science Foundation of China (81871640);

National Natural Science Foundation of China (82172255)

More Information

Corresponding author: ZHANG Jiming, jmzhang@fudan.edu.cn (ORCID: 0000-0001-5820-950X)

摘要

摘要: HDV感染的流行率和危害程度一直被低估，低筛查率和低诊断率或带来严重疾病负担。HDV RNA作为病毒复制的直接证据，对于丁型肝炎的诊断和管理具有重要意义。本文总结了HDV RNA检测的临床意义，并介绍了检测方法的进展，以期促进丁型肝炎的筛查和诊断。
- 丁型肝炎 /
- RNA, 病毒 /
- 诊断 /
- 逆转录聚合酶链反应
Abstract: The prevalence and severity of hepatitis D virus (HDV) infection have always been underestimated, and the low screening and diagnosis rates may bring severe disease burden. HDV RNA, as the direct evidence of viral replication, is of great importance for the diagnosis and management of hepatitis D. This article summarizes the clinical significance of HDV RNA detection and introduces the advances in detection methods, in order to facilitate the screening and diagnosing of hepatitis D.
- Hepatitis D /
- RNA, Viral /
- Diagnosis /
- Reverse Transcriptase Polymerase Chain Reaction

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参考文献(59)

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