胆囊运动亢进的研究进展

梁文平; 罗丹; 刘博; 薛东波; 马骉

doi:10.3969/j.issn.1001-5256.2022.10.043

胆囊运动亢进的研究进展

DOI: 10.3969/j.issn.1001-5256.2022.10.043

哈尔滨医科大学附属第一医院微创胆道外科，哈尔滨 150001

基金项目:

黑龙江省自然科学基金 (LH2021H050)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：梁文平负责课题设计，资料分析，撰写论文；罗丹堃、刘博参与收集数据，修改论文；薛东波、马骉负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
马骉，mabiao@hrbmu.edu.cn

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出版历程
- 收稿日期: 2022-03-07
- 录用日期: 2022-06-02
- 出版日期: 2022-10-20

The progression of biliary hyperkinesia research

Minimally Invasive Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

Research funding:

Heilongjiang Provincinal Natural Science Foundation of China (LH2021H050)

More Information

Corresponding author: MA Biao, mabiao@hrbmu.edu.cn(ORCID: 0000-0002-7429-908x)

摘要

摘要: 近年来，消化系统疾病的发病率逐年升高，胆道运动障碍也愈发受到人们关注，特别是其中所包含的胆囊运动亢进。本文从国内外该领域研究现状出发，对胆囊运动亢进的基本概念、流行病学、发病机制、病理、临床与影像学表现、诊断与治疗相关临床研究进展进行了系统阐述，并在此基础上对未来相关研究方向给出建议。
- 胆囊运动障碍 /
- 胆道疾病 /
- 胆囊疾病
Abstract: In recent years, the incidence of digestive disorders has risen steadily. Among which, biliary dyskinesia, particularly biliary hyperkinesia, has become a growing concern. The basic concept, epidemiology, pathogenesis, pathology, clinical and imaging manifestations, diagnosis, and treatment of biliary hyperkinesia are systematically reviewed in this paper based on the current status of research in this field worldwide. On this basis, prospective future research directions are also provided.
- Biliary Dyskinesia /
- Biliary Tract Diseases /
- Gallbladder Diseases

HTML全文

图 1 胆囊运动亢进的信号通路

Figure 1. Signaling pathways in biliary hyperkinesia

下载: 全尺寸图片幻灯片

图 2 胆囊运动亢进患者的诊断流程

Figure 2. Diagnostic process for patients with biliary hyperkinesia

下载: 全尺寸图片幻灯片

表 1 胆囊运动亢进病理学特点

Table 1. Pathologic features of biliary hyperkinesia

文献	年份	样本量 (例)	年龄 (岁)	平均 GEEF¹⁾	病理学特点
文献	年份	样本量 (例)	年龄 (岁)	平均 GEEF¹⁾	慢性胆囊炎[例(%)]	其他 (例)	正常 (例)
Saurabh等^[4]	2019	32	46±12	92%	29(90)	2	1
Wright等^[19]	2019	40	-	＞80%	40(100)	0	0
Pillenahalli等^[11]	2020	21	39±14	＞80%	21(100)	0	0
Nasri等^[5]	2021	59	48.81±15.62	88.53%	27(75)	3	6
注：1)所取样本中所有患者GBEF的平均值。-，数据缺如。

下载: 导出CSV

表 2 腹腔镜胆囊切除术对胆囊运动亢进患者的症状缓解情况

Table 2. Relief of symptoms in patients with biliary hyperkinesia by laparoscopic cholecystectomy

文献作者	年份	样本量(例)	年龄(岁)	平均GBEF¹⁾	症状缓解[例(%)]
Holes-Lewis等^[52]	2009	28	-	＞80%	27/28(96.4)
Law等^[53]	2014	26	-	＞80%	18/26(69.2)
Saurabh等^[4]	2019	32	46±12	92%	28/31(90.3)
Wright等^[19]	2019	40	-	＞80%	36/40(90.0)
Nasri等^[5]	2019	59	48.81±15.62	88.53%	51/59(86.4)
Gazzetta等^[18]	2019	77	-	＞80%	70/77(90.1)
Pillenahalli等^[11]	2020	21	39±14	＞80%	18/21(86.0)
Bosley等^[48]	2020	18	15.7±1.8	91.6%±5.2%	14/17(82.4)
注：1)所有样本GBEF之和/样本量。-，数据缺如。

下载: 导出CSV

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