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肝纤维化发生机制及其中药逆转治疗的研究进展

刘世恒 赵素贤 张玉果

引用本文:
Citation:

肝纤维化发生机制及其中药逆转治疗的研究进展

DOI: 10.3969/j.issn.1001-5256.2022.10.033
基金项目: 

河北省医学适用技术跟踪项目 (G2018041)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:刘世恒负责课题设计,资料分析,撰写论文; 赵素贤参与修改论文; 张玉果负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    张玉果,15930173200@126.com

Recent research progress and mechanisms on Traditional Chinese Medicine reversal therapy of liver fibrosis

Research funding: 

Hebei Province Medical Technology, Tracking, and Application Project (G2018041)

More Information
  • 摘要: 肝纤维化是指在各种病因作用下,肝星状细胞被激活,分泌大量的细胞外基质,最终导致肝脏纤维化。早期逆转肝纤维化可以阻止疾病进一步发展,减少终末期肝病和肝癌的发生,本文分别介绍了肝血窦内皮细胞(LSEC)、Notch信号通路、YAP/TAZ信号通路、细胞自噬在逆转肝纤维化方面的作用机制,并列举其各自机制下抗肝纤维化的中药治疗研究进展,以期为逆转肝纤维化提供新的研究思路及中药治疗方法。

     

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  • 收稿日期:  2022-03-11
  • 录用日期:  2022-04-29
  • 出版日期:  2022-10-20
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