抗gp210抗体在原发性胆汁性胆管炎中的产生机制与检测价值

张继红; 李素领

doi:10.3969/j.issn.1001-5256.2022.06.041

抗gp210抗体在原发性胆汁性胆管炎中的产生机制与检测价值

DOI: 10.3969/j.issn.1001-5256.2022.06.041

张继红¹,
李素领^2, , ,

1.
河南中医药大学第一临床医学院，郑州 450000
2.
河南中医药大学第一附属医院脾胃肝胆科，郑州 450000

基金项目:

河南省中医药科学研究专项课题 (20-21ZY1011)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：张继红负责拟定提纲、收集文献及撰写论文；李素领负责指导撰写论文、修改论文，并最后定稿。

详细信息

通信作者:
李素领，hk-lsl@163.com

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出版历程
- 收稿日期: 2021-09-26
- 录用日期: 2021-10-28
- 出版日期: 2022-06-20

Production mechanism and detection value of anti-gp210 antibody in primary biliary cholangitis

Jihong ZHANG¹,
Suling LI^{2
, ,
,}

1.
The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450000, China
2.
Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China

Research funding:

Special Subject of Scientific Research on Traditional Chinese Medicine in Henan Province (20-21ZY1011)

More Information

Corresponding author: LI Suling, hk-lsl@163.com(ORCID: 0000-0002-5211-1330)

摘要

摘要: 原发性胆汁性胆管炎(PBC)是自身免疫性肝病之一，多数患者早期无明显临床表现，出现症状已至中晚期，尽早明确诊断及评估预后是非常必要的。抗gp210抗体对于诊断PBC及预测疾病进展有重要价值，检测该抗体可以优化PBC评分系统。本文总结评述了抗gp210抗体在PBC中的产生机制及检测的具体价值。
- 肝硬化, 胆汁性 /
- 抗体 /
- 诊断 /
- 预后
Abstract: Primary biliary cholangitis (PBC) is one of the autoimmune liver diseases, and most patients have no obvious clinical manifestations in the early stage and have reached the advanced stage when symptoms appear. Therefore, it is necessary to make a confirmed diagnosis and evaluate prognosis as early as possible. Anti-gp210 antibody is of great value in the diagnosis of PBC and the prediction of disease progression, and the detection of anti-gp210 antibody can help to optimize the PBC scoring system. This article reviews the production mechanism and detection value of anti-gp210 antibody in PBC.
- Liver Cirrhosis, Biliary /
- Antibodies /
- Diagnosis /
- Prognosis

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参考文献(39)

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