肝硬化门静脉高压的无创筛查管理

张晓丰; 陈金军

doi:10.3969/j.issn.1001-5256.2022.06.002

肝硬化门静脉高压的无创筛查管理

DOI: 10.3969/j.issn.1001-5256.2022.06.002

张晓丰^{1, 2},
陈金军^{1, 2, 3, , ,}

1.
南方医科大学南方医院肝病中心，广州 510515
2.
南方医科大学南方医院增城分院肝病科，广州 511300
3.
广东省肝脏疾病研究所，广州 510515

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：张晓丰负责查找文献，撰写文稿；陈金军负责确定写作思路，指导文章撰写及最后定稿。

详细信息

通信作者:
陈金军，chjj@smu.edu.cn

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出版历程
- 收稿日期: 2022-03-06
- 录用日期: 2022-04-12
- 出版日期: 2022-06-20

Noninvasive screening and management of cirrhotic portal hypertension

Xiaofeng ZHANG^{1, 2},
Jinjun CHEN^{1, 2, 3
, ,
,}

1.
Hepatology Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
2.
Department of Hepatology, Zengcheng Branch of Nanfang Hospital, Southern Medical University, Guangzhou 511300, China
3.
Hepatology Institute of Guangdong Province, Guangzhou 510515, China

More Information

Corresponding author: CHEN Jinjun, chjj@smu.edu.cn (ORCID: 0000-0003-4275-9149)

摘要

摘要: 门静脉高压相关并发症是进展期慢性肝病(ACLD)患者死亡的主要原因。肝静脉压力梯度为评估门静脉高压的金标准，上消化道内镜检查是筛查和评估食管胃静脉曲张及严重程度的重要手段；两者均为侵入性操作，不便于门静脉高压的筛查和监测。瞬时弹性成像、声辐射力脉冲弹性成像、剪切波弹性成像等无创方式，可用于ACLD患者门静脉高压，尤其是临床显著性门静脉高压的筛查、分层诊断和监测。
- 肝硬化 /
- 高血压, 门静脉 /
- 弹性成像技术
Abstract: Portal hypertension-related complications are the major cause of death in patients with advanced chronic liver disease (ACLD). Hepatic venous pressure gradient is the golden standard for assessing portal hypertension, and upper gastrointestinal endoscopy is an important method for screening and assessing esophageal and gastric varices and its severity; both methods are invasive and inappropriate for portal hypertension screening and monitoring. Noninvasive approaches, such as transient elastography, acoustic radiation force impulse, and shear wave elastography, have been used for the evaluation of portal hypertension in ACLD patients, especially the screening, stratified diagnosis, and monitoring of clinically significant portal hypertension.
- Liver Cirrhosis /
- Hypertension, Portal /
- Elasticity Imaging Techniques

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参考文献(35)

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