中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

肝移植术后自发性肝破裂出血1例报告

马健 何力宏 王凌云 翟亚楠 李汛 张磊

引用本文:
Citation:

肝移植术后自发性肝破裂出血1例报告

DOI: 10.3969/j.issn.1001-5256.2022.04.030
基金项目: 

兰州大学第一医院院内基金 (ldyyyn2019-105);

甘肃省高等学校创新基金 (2021B-013)

伦理学声明:本例报告已获得患者知情同意。
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:马健负责拟定写作思路, 资料分析,撰写论文; 何力宏、王凌云、翟亚楠负责资料采集, 修改论文; 张磊、李汛负责指导撰写文章, 修改论文并最后定稿。
详细信息
    通信作者:

    李汛,lxdr21@126.com

    张磊,drzhanglei@lzu.edu.cn

A case of spontaneous hepatic rupture and hemorrhage after liver transplantation

Research funding: 

Hospital Fund of the First Hospital of Lanzhou University (ldyyyn2019-105);

Innovation Foundation of the Higher Education Institutions of Gansu Province, China (2021B-013)

More Information
  • 图  1  围手术期肝功能主要指标变化

    Figure  1.  Profile of the perioperative liver function

    图  2  围手术期INR变化

    Figure  2.  Profile of the perioperative lNR

    图  3  围手术期凝血指标变化

    Figure  3.  Profile of the perioperative coagulation function

    图  4  围手术期Hb、PLT指标变化

    Figure  4.  Profile of the perioperative Hb and PLT

    图  5  术后第10天急查B超及全腹CT结果

    注:a,超声示腹腔积血; b,CT示肝尾状叶增大、出血; c,CT示小网膜囊积血; d,CT示积血自肝尾状叶延伸至小网膜囊。蓝色箭头示肝尾状叶区,红色箭头示积血。

    Figure  5.  Ultrasonography and abdominal CT scan on posttransplant 10th day

    图  6  剖腹探查所见

    注:可见尾状叶破裂出血,行缝扎止血。蓝色箭头示肝尾状叶区,黄色箭头示肝动脉。

    Figure  6.  Intraoperative findings

  • [1] ADAM R, KARAM V, CAILLIEZ V, et al. 2018 Annual Report of the European Liver Transplant Registry (ELTR) - 50-year evolution of liver transplantation[J]. Transpl Int, 2018, 31(12): 1293-1317. DOI: 10.1111/tri.13358.
    [2] KIM DS, LEE SG, SUNG GB, et al. Management of subcapsular hematoma of the graft after living donor liver transplantation[J]. Liver Transpl, 2006, 12(7): 1124-1128. DOI: 10.1002/lt.20791.
    [3] MOON DB, LEE SG, HWANG S, et al. Massive subcapsular hematoma of liver graft after living donor liver transplantation: A case report[J]. Transplant Proc, 2003, 35(4): 1469-1472. DOI: 10.1016/S0041-1345(03)00471-8.
    [4] DING ZY, CAI B, ZHAO Y. Experience in the diagnosis and intraoperative treatment of liver rupture after transplantation[J]. Chin J Modern Operative Surg, 2010, 14(6): 481. https://www.cnki.com.cn/Article/CJFDTOTAL-XDSS201006027.htm

    丁忠阳, 蔡兵, 赵翼. 移植肝脏破裂的诊断和术中处理体会[J]. 中国现代手术学杂志, 2010, 14(6): 481. https://www.cnki.com.cn/Article/CJFDTOTAL-XDSS201006027.htm
    [5] SENZOLO M, BURRA P, CHOLONGITAS E, et al. New insights into the coagulopathy of liver disease and liver transplantation[J]. World J Gastroenterol, 2006, 12(48): 7725-7736. DOI: 10.3748/wjg.v12.i48.7725.
    [6] HSU SC, THORAT A, POON KS, et al. Management of liver allograft trauma resulting in massive subcapsular hematoma after living donor liver transplantation: Can we salvage the liver allograft?[J]. Ann Transplant, 2017, 22: 1-8. DOI: 10.12659/aot.901006.
    [7] BROCKMANN JG. Liver damage during organ donor procurement in donation after circulatory death compared with donation after brain death (Br J Surg 2013; 100: 381-386)[J]. Br J Surg, 2013, 100(3): 386-387. DOI: 10.1002/bjs.9010.
    [8] Chinese Society of Organ Transplantation, Chinese Medical Association. Technical specifications for obtaining donor liver for liver transplantation in China (version 2019)[J]. J Clin Hepatol, 2019, 35(12): 2700-2702. DOI: 10.3969/j.issn.1001-5256.2019.12.011.

    中华医学会器官移植学分会. 中国肝移植供肝获取技术规范(2019版)[J]. 临床肝胆病杂志, 2019, 35(12): 2700-2702. DOI: 10.3969/j.issn.1001-5256.2019.12.011.
    [9] TANG R, WU GD, YANG W, et al. Management of graft laceration in orthotopic liver transplantation[J]. J Hepatopancreatobiliary Surg, 2021, 33(6): 321-324. DOI: 10.11952/j.issn.1007-1954.2021.06.001.

    汤睿, 吴广东, 杨威, 等. 原位肝移植供肝撕裂伤的处理[J]. 肝胆胰外科杂志, 2021, 33(6): 321-324. DOI: 10.11952/j.issn.1007-1954.2021.06.001.
    [10] WANG ZH, GUO WZ. The diagnosis and treatment of vascular complications following liver transplantAtion[J]. Chin J Organ Transplant, 2019, 40(11): 641-642. DOI: 10.3760/cma.j.issn.0254-1785.2019.11.001.

    王智慧, 郭文治. 肝移植术后血管并发症的诊断与治疗[J]. 中华器官移植杂志, 2019, 40(11): 641-642. DOI: 10.3760/cma.j.issn.0254-1785.2019.11.001.
    [11] NISSEN NN, GELLER SA, KLEIN A, et al. Percutaneous liver biopsy after living donor liver transplantation resulting in fulminant hepatic failure: The first reported case of hepatic compartment syndrome[J]. J Transplant, 2010, 2010: 273578. DOI: 10.1155/2010/273578.
    [12] LUPASCU C, APOPEI O, VLAD N, et al. Early spontaneous graft intra- and perihepatic hematoma after liver transplantation[J]. Chirurgia (Bucur), 2017, 112(3): 342-348. DOI: 10.21614/chirurgia.112.3.342.
    [13] Perioperative Management Group, Chinese Society of Organ Transplantation, Chinese Medical Association. Expert consensus on perioperative management of coagulation function in adult liver transplant recipients[J/CD]. Prac J Organ Transplant(Electronic Version), 2021, 9(2): 89-94. DOI: 10.3969/j.issn.2095-5332.2021.02.001.

    中华医学会器官移植学分会围手术期管理学组. 成人肝移植受者围术期凝血功能管理专家共识(2021版)[J/CD]. 实用器官移植电子杂志, 2021, 9(2): 89-94. DOI: 10.3969/j.issn.2095-5332.2021.02.001.
    [14] WANG GG, LI Q, WANG S, et al. Dynamic changes of thromboelastography and coagulation function parameters before and after liver transplantation and its significance for guidance of blood transfusion[J]. J Prac Hepatol, 2020, 23(6): 901-904. https://www.cnki.com.cn/Article/CJFDTOTAL-GBSY202006038.htm

    王广耕, 李茜, 王姗, 等. 肝移植患者凝血功能和血栓弹力图指标动态变化[J]. 实用肝脏病杂志, 2020, 23(6): 901-904. https://www.cnki.com.cn/Article/CJFDTOTAL-GBSY202006038.htm
    [15] Branch of Organ Transplantation of Chinese Medical Association. Diagnosis and treatment specification for postoperative complications after liver transplantation in China (2019 edition)[J]. Ogran Transplantation, 2021, 12(2): 129-133. DOI: 10.3969/j.issn.1674-7445.2021.02.002.

    中华医学会器官移植学分会. 中国肝移植术后并发症诊疗规范(2019版)[J]. 器官移植, 2021, 12(2): 129-133. DOI: 10.3969/j.issn.1674-7445.2021.02.002.
    [16] CHANG ZF, LI Q, LIU FY, et al. Endovascular treatment of liver rupture and bleeding[J/CD]. Chin J Interv Radiol(Electronic Edition), 2015, 3(2): 95-99. DOI: 10.3877/cma.j.issn.2095-5782.2015.02.011.

    常中飞, 李强, 刘凤永, 等. 血管内介入治疗肝脏破裂出血[J/CD]. 中华介入放射学电子杂志, 2015, 3(2): 95-99. DOI: 10.3877/cma.j.issn.2095-5782.2015.02.011.
    [17] KOZAR RA, CRANDALL M, SHANMUGANATHAN K, et al. Organ injury scaling 2018 update: Spleen, liver, and kidney[J]. J Trauma Acute Care Surg, 2018, 85(6): 1119-1122. DOI: 10.1097/TA.0000000000002058.
  • 加载中
图(6)
计量
  • 文章访问数:  384
  • HTML全文浏览量:  205
  • PDF下载量:  29
  • 被引次数: 0
出版历程
  • 收稿日期:  2021-07-26
  • 出版日期:  2022-04-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回