甲巯咪唑诱导自身免疫样药物性肝损伤1例报告

崔仕元; 郑美芳; 张玮; 王珊珊; 高润平

doi:10.3969/j.issn.1001-5256.2021.12.032

甲巯咪唑诱导自身免疫样药物性肝损伤1例报告

DOI: 10.3969/j.issn.1001-5256.2021.12.032

吉林大学第一医院肝胆胰内科，长春 130021

基金项目:

国家自然科学基金面上项目 (81770629)

详细信息

通信作者:
高润平，gao_runping@126.com

中图分类号: R575.1
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- 文章访问数: 424
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- 被引次数: 0
出版历程
- 收稿日期: 2021-04-16
- 录用日期: 2021-05-31
- 出版日期: 2021-12-20

A case of autoimmune-like methimazole-induced liver injury

Department of Hepatology, The First Hospital of Jilin University, Changchun 130021, China

Research funding:

National Natural Scientific Foundation of China (81770629)

摘要

- 乙型肝炎, 慢性 /
- 甲状腺功能亢进症 /
- 化学性与药物性肝损伤 /
- 甲巯咪唑
- Hepatitis B, Chronic /
- Hyperthyroidism /
- Chemical and Drug Induced Liver Injury /
- Methimazole

HTML全文

图 1 患者住院期间治疗措施及重要指标变化趋势

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图 2 肝活检病理结果

注：a.部分临近汇管区相连分隔周围肝实质，间质轻度纤维化(网织+Masson染色)；b.汇管区可见淋巴浆细胞浸润，明显界面炎，可见玫瑰花样肝细胞(箭头)，部分肝细胞可见胆色素颗粒和毛细胆管胆栓(HE染色)。

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参考文献(17)

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