肝原发性纤维肉瘤误诊为肝脓肿1例报告

朱刘洋; 侯建存; 杨龙; 童文; 张雅敏

doi:10.3969/j.issn.1001-5256.2021.07.037

肝原发性纤维肉瘤误诊为肝脓肿1例报告

DOI: 10.3969/j.issn.1001-5256.2021.07.037

1.
天津医科大学一中心临床学院，天津 300070
2.
天津市第一中心医院肝胆外科，天津 300192

基金项目:

天津市科技计划项目 (19ZXDBSY00010)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：朱刘洋负责资料分析，查阅文献，撰写论文；杨龙、侯建存负责收集数据，修改论文；童文负责收集分析数据；张雅敏负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
侯建存，houjc@nankai.edu.cn

中图分类号: R735.7
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- 被引次数: 0
出版历程
- 收稿日期: 2020-11-19
- 录用日期: 2020-12-22
- 出版日期: 2021-07-20

Primary fibrosarcoma of the liver misdiagnosed as hepatic abscess: A case report

1.
The First Central Clinical College of Tianjin Medical University, Tianjin 300070, China
2.
Department of Hepatobiliary Surgery, Tianjin First Central Hospital, Tianjin 300192, China

Research funding:

Science and Technology Planning Projects of Tianjin (19ZXDBSY00010)

摘要

- 肝肿瘤 /
- 纤维肉瘤 /
- 肝脓肿 /
- 误诊
- Liver Neoplasms /
- Fibrosarcoma /
- Liver Abscess /
- Diagnostic Errors

HTML全文

图 1 术前增强CT检查结果

注：a, 平扫可见肝右叶大片低密度影，大小约13 cm×6 cm，部分突出至右侧膈下；b, 动脉期病变周围轻度不均匀强化，其内可见不规则更低密度区；c, 静脉期正常肝实质强化，病变区域为相对低密度；d, 延迟期病变持续渐进性强化，向中心填充。

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图 2 肝脏三维重建图像

注：绿色部分为保留肝脏，体积为582.99 cm³，箭头示尾状叶肿物。

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图 3 大体标本

注：a，肝右叶肿物；b，膈肌肿物。

下载: 全尺寸图片幻灯片

图 4 术后病理结果

注：a，HE染色可见梭形瘤细胞呈束状交错排列，细胞核深染，可见分裂像(×100)；b，免疫组化结果Vimentin阳性(×100)。

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参考文献(13)

[1]	FOLPE AL. Fibrosarcoma: A review and update[J]. Histopathology, 2014, 64(1): 12-25. DOI: 10.1111/his.12282.
[2]	DOYLE LA. Sarcoma classification: An update based on the 2013 World Health Organization classification of tumors of soft tissue and bone[J]. Cancer, 2014, 120(12): 1763-1774. DOI: 10.1002/cncr.28657.
[3]	KELLE S, PAETSCH I, NEUSS M, et al. Primary fibrosarcoma of the liver infiltrating the right atrium of the heart[J]. Int J Cardiovasc Imaging, 2005, 21(6): 655-658. DOI: 10.1007/s10554-005-2907-2.
[4]	ALI S, SHAH P, SHAH UJ, et al. Primary fibrosarcoma of the liver: We don't know much: A case report[J]. Case Rep Gastroenterol, 2008, 2(3): 384-389. DOI: 10.1159/000161563.
[5]	QIU SS, DENG X, LI DQ, et al. Primary fibrosarcoma of the liver: A case report[J]. J Pract Oncol, 2010, 25(4): 463-464. https://www.cnki.com.cn/Article/CJFDTOTAL-SYZZ201004030.htm 邱莎莎, 邓晓, 李代强, 等. 肝脏原发性纤维肉瘤1例报道[J]. 实用肿瘤杂志, 2010, 25(4): 463-464. https://www.cnki.com.cn/Article/CJFDTOTAL-SYZZ201004030.htm
[6]	SU ZX, LI LQ, XIAO KY. A case report of liver fibrosarcoma[J]. Chin J Gen Surg, 2006, 21(11): 837. DOI: 10.3760/j.issn:1007-631X.2006.11.035. 苏智雄, 黎乐群, 肖开银. 肝纤维肉瘤一例[J]. 中华普通外科杂志, 2006, 21(11): 837. DOI: 10.3760/j.issn:1007-631X.2006.11.035.
[7]	ZHANG B, ZHONG DW, HU JX, et al. A case report of liver fibrosarcoma[J]. Chin J Pract Surg, 2009, 29(10): 849. DOI: 10.3321/j.issn:1005-2208.2009.10.035 张斌, 钟德玝, 胡继雄, 等. 肝纤维肉瘤1例[J]. 中国实用外科杂志, 2009, 29(10): 849. DOI: 10.3321/j.issn:1005-2208.2009.10.035
[8]	YU RS, CHEN Y, JIANG B, et al. Primary hepatic sarcomas: CT findings[J]. Eur Radiol, 2008, 18(10): 2196-2205. DOI: 10.1007/s00330-008-0997-7.
[9]	WEITZ J, KLIMSTRA DS, CYMES K, et al. Management of primary liver sarcomas[J]. Cancer, 2007, 109(7): 1391-1396. DOI: 10.1002/cncr.22530.
[10]	WANG J, CHEN QW, ZHENG GR, et al. Evolution and development of surgical treatment for liver cancer[J]. J Clin Hepatol, 2020, 36(10): 2161-2166. DOI: 10.3969/j.issn.1001-5256.2020.10.001. 王捷, 陈茄威, 郑国荣, 等. 肝癌外科治疗的演变与发展[J]. 临床肝胆病杂志, 2020, 36(10): 2161-2166. DOI: 10.3969/j.issn.1001-5256.2020.10.001.
[11]	ZHOU F, HUANG HZ, ZHOU MT, et al. Surgical treatment and chemotherapy of adult primary liver sarcoma: Experiences from a single hospital in China[J]. Dig Surg, 2019, 36(1): 46-52. DOI: 10.1159/000486454.
[12]	MEYER M, SEETHARAM M. First-line therapy for metastatic soft tissue sarcoma[J]. Curr Treat Options Oncol, 2019, 20(1): 6. DOI: 10.1007/s11864-019-0606-9.
[13]	QIAN XH, GAO BQ, WANG WL. Primary hepatic sarcomatous carcinoma misdiagnosed as liver abscess: A case report[J]. J Clin Hepatol, 2020, 36(1): 158-160. DOI: 10.3969/j.issn.1001-5256.2020.01.035. 钱晓晖, 高炳强, 王伟林. 原发性肝肉瘤样癌误诊为肝脓肿1例报告[J]. 临床肝胆病杂志, 2020, 36(1): 158-160. DOI: 10.3969/j.issn.1001-5256.2020.01.035.