肝细胞癌微血管侵犯的术后辅助治疗

龚天乐; 岳平; 严俊; 李汛

doi:10.3969/j.issn.1001-5256.2021.03.037

肝细胞癌微血管侵犯的术后辅助治疗

DOI: 10.3969/j.issn.1001-5256.2021.03.037

龚天乐¹,
岳平^{1, 2, 3, 4, 5},
严俊^{2, 3, 4, 5},
李汛^{1, 2, 3, 4, 5, ,}

1.
兰州大学第一临床医学院, 兰州 730000
2.
兰州大学第一医院普外科, 兰州 730000
3.
甘肃省中西医结合肝病治疗中心, 兰州 730000
4.
甘肃省生物治疗与再生医学重点实验室, 兰州 730000
5.
甘肃省肝胆胰外科研究所, 兰州 730000

基金项目:

甘肃省科技重大专项 (1602FKDA001);

兰州市人才创新创业项目 (2016-RC-57);

甘肃省卫生行业科研计划项目 (GSWSKY-2015-49);

兰州市城关区科技局项目 (2017SHFZ0014)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：龚天乐负责论文设计、资料收集和论文撰写；岳平参与论文设计和论文修改；严俊参与论文设计和文献分析；李汛参与论文思路设计和负责论文审改定稿。

详细信息

作者简介:
龚天乐(1994—)，男，主要从事肝癌相关研究

通信作者:
李汛，lxdr21@126.com

中图分类号: R735.7
计量
- 文章访问数: 549
- HTML全文浏览量: 260
- PDF下载量: 57
- 被引次数: 0
出版历程
- 收稿日期: 2020-08-25
- 录用日期: 2020-10-09
- 出版日期: 2021-03-20

Adjuvant therapies after surgery for hepatocellular carcinoma with microvascular invasion

Tianle GONG¹,
Ping YUE^{1, 2, 3, 4, 5},
Jun YAN^{2, 3, 4, 5},
Xun LI^{1, 2, 3, 4, 5
, ,}

1.
The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China
2.
Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China
3.
Gansu Province Liver Center of Integrated Traditional Chinese and West Medicine, Lanzhou 730000, China
4.
Gansu Province Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou 730000, China
5.
Hepatopancreatobiliary Surgery Institute of Gansu Province, Lanzhou 730000, China

摘要

摘要: 肝细胞癌(HCC)术后的高复发率不容忽视，有关HCC术后的辅助治疗在国际上尚无统一的共识意见或指南推荐。现有研究表明微血管侵犯是HCC术后复发的高危因素之一，对于伴有微血管侵犯的HCC患者，术后适时的辅助治疗可能会推迟复发时间，使患者获益。现阶段通过辅助治疗预防HCC术后复发及延长生存期日益受到关注。就近年来HCC微血管侵犯术后辅助治疗的研究进展进行综述，以期对伴有微血管侵犯的HCC术后患者的辅助治疗提供参考和帮助。
- 癌, 肝细胞 /
- 微血管侵犯 /
- 肿瘤辅助疗法
Abstract: The high recurrence rate of hepatocellular carcinoma (HCC) after surgery cannot be ignored, but there are still no consensus statements and guideline recommendations for adjuvant therapies after HCC surgery. Current studies have shown that microvascular invasion is one of the high-risk factors for postoperative recurrence of HCC, and for HCC patients with microvascular invasion, timely postoperative adjuvant therapy may delay the time to recurrence and bring benefits to patients. At this stage, the prevention of postoperative recurrence of HCC and the prolongation of survival time through adjuvant therapy have attracted more and more attention. This article reviews the research advances in adjuvant therapy after surgery for HCC with microvascular invasion in recent years, in order to provide reference and help for postoperative adjuvant therapies for HCC patients with microvascular invasion.
- Carcinoma, Hepatocellular /
- Microvascular Invasion /
- Neoadjuvant Therapy

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参考文献(50)

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